Hauswand des DRFZ

Core Facilities

The Core Facilities at the DRFZ provide all researchers with access to the most advanced equipment and technologies. It encompasses the flow cytometry and cell sorting unit, Regine-von-Ramin Laboratory for Molecular Rheumatology, Central Laboratory, Bioinformatics, Immune Monitoring, and Imaging. These facilities consist of scientific equipments that are used among all the research groups at the DRFZ to collect and analyze data, allowing researchers to conduct studies at the molecular and cellular level.

  • The Flow Cytometry Core Facility (FCCF) provides scientists the opportunity to conduct flow cytometry and cell sorting, which are essential for immunological and cell biological experiments.
  • The Ramin Laboratory for Molecular Rheumatology (RvR-lab), named after the generous legacy of Mrs. Regine von Ramin, offers technologies that allow for gene expression analysis and laser capture microdissection (LCM). These are important tools in molecular analysis at the DNA, RNA, and protein level, which can provide new biomarkers and target molecules for diagnosis and therapy of rheumatic diseases.
  • The Central Laboratory focuses on the production and supply of materials that are needed for doing experimental cell-biological research.
  • The central laboratory manages the whole infrastucture of the DRFZ.
  • Bioinformatics primarily focuses on high content data, such as gene expression profiling. It includes access to an integrative database (http://www.bioretis-analysis.de) for sharing, storage and analyzing gene expression data. The data collected from the RvR-lab and the immune monitoring departments are preferentially analyzed here in Bioinformatics facility.
  • Immune monitoring makes it possible to detect cellular modifications caused by inflammation within the blood. Using the information from FCCF, the data collected provides scientists with information about the immune state of a patient.
  • Imaging provides the latest achievement of microscopic visualization with the Multi-Photon Laser Scanning Microscope. This latest technology provides three-dimensional images without damaging the vital samples.