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Animal Facility

Animal welfare and good research go hand in hand

Introduction
Members
Further information
Cooperation partners
Selected Publications

Although the development of methods replacing animal experiments is constantly advancing, some scientific questions still require the use of animal models. The complexity of a living organism is indispensable, especially in understanding multifactorial diseases such as autoimmune disorders, in which a multitude of organs and cell types are involved.

Therefore, the DRFZ runs a state of the art animal facility and houses numerous different mouse strains. Genetically modified mice are an invaluable component of biomedical research. The facility is divided into an experimental facility in Berlin Mitte and a separate breeding area in Berlin Marienfelde. Specially trained animal care takers and veterinarians ensure optimal husbandry conditions and a seamless monitoring of the animals in favour of animal welfare.

All mice are kept under so-called SPF (specified pathogen free) conditions to ensure that they are free from pathogens which could interfere with their well-being and also with experimental studies. For this purpose, the facility is equipped with personnel locks and all supply material is thoroughly autoclaved before being introduced to the facility. Moreover, mice undergo a regular health-monitoring in order to detect potentially pathogenic microorganisms.

As a part of the Leibniz Association, the DRFZ is obliged to be transparent and openly communicate with the public regarding animal experimentation. It is a member of the German research institutions´ information initiative „Tierversuche verstehen“ (engl.: understanding animal research; www.tierversuche-verstehen.de), which informs about animal experiments conductedat publicly funded research institutions and promotes the dialogue between science and public. Scientists involved in animal experiments at the DRFZ are obliged to follow the 3R principle – replace, reduce, refine – in order to minimize any animal distress in the experiment and to improve animal welfare. They are consulted by independent animal welfare officers who furthermore ensure and supervise their adherence to respective rules and regulations.

The institute’s animal welfare committee* meets on a regular basis and supports the animal welfare officers in their duties and their animal welfare surveillance.

Furthermore, the DRFZ provides a training programme conducted by veterinarians which educates scientists in compliance with European Union and German animal welfare legislation and under close consideration of animal welfare. This training programme is comprised of a theoretical and practical part after which successful participation is officially certified. For all employees working with animals, regular training and further education concerning laboratory animal protection and the 3R principle is offered.

* The animal welfare committee consists of animal welfare officers, animal care staff and scientists working experimentally.

Keywords
Animal welfare, animal protection, 3R principle

Veterinarian Dr. med. vet. Anja Schulz Phone +49-(0)30-28460-0 info@drfz.de more
Animal Welfare Officer Anna Pfeffer Phone +49 30 28460 - 0 info@drfz.de more
Group Leader

Contact: info@drfz.de

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Animal facility management:
Dr. med. vet. Anja Schulz

Animal welfare officers:
Anna Pfeffer

Administration and Technical Staff:
Gruczek
Hoffmann
P. Hong
Kasprzak
Streckert
Theißig
Thiemann

Trainee
Acosta-Ruediger

Group Leader

Contact: info@drfz.de

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Animal experiments in the Leibniz Association
Leibniz researchers conduct basic and applied research with the aim of developing ways of solving the major challenges facing society. Around 20 Leibniz Institutes, especially those in the field of life sciences, rely on animal experiments for their work. They hope, through their basic research, to make new treatments, drugs and technologies available to tackle widespread diseases, but also to improve animal wellbeing, for example in farming.
Initiative "Tierversuche verstehen" - in German only
„Tierversuche verstehen“ ist eine Initiative der deutschen Wissenschaft, koordiniert von der Allianz der Wissenschaftsorganisationen. Sie informiert umfassend, aktuell und faktenbasiert über Tierversuche an öffentlich geförderten Forschungseinrichtungen.
Group Leader

Contact: info@drfz.de

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Dr. Uwe Klemm, Experimental Animals, Max Planck Institute for Infection Biology, Berlin

Dr. Geert Michel, Transgen Facility, FEM, Charité University Medicine Berlin

Ronald Naumann, Transgenic Core Facility, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden

Frank Zimmermann, Biotechnology Laboratory, University Heidelberg

Group Leader

Contact: info@drfz.de

Continue to Selected Publications

Ullmann K, Jourdan T, Kock M, Unger J, Schulz A, Thöne-Reineke C, Abramjuk A (2018): Recommendations for the development and use of Score Sheets as a tool for applied refinement. Berl Münch Tierärztl Wochenschr 131(7/8):292-298.

Group Leader

Contact: info@drfz.de

Continue to Introduction