{"id":1685,"date":"2024-12-04T10:36:47","date_gmt":"2024-12-04T10:36:47","guid":{"rendered":"https:\/\/www.drfz.de\/?post_type=head&#038;p=1685"},"modified":"2025-06-18T14:21:44","modified_gmt":"2025-06-18T14:21:44","slug":"eicke-latz","status":"publish","type":"head","link":"https:\/\/www.drfz.de\/en\/koepfe\/eicke-latz\/","title":{"rendered":"Prof. Dr. med. Eicke Latz"},"content":{"rendered":"\n<section class=\"wp-block-group alignwide\">\n<h2 class=\"wp-block-heading toc-item\" id=\"biosketch\">Biosketch<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Prof. Dr. (med.) Eicke Latz studied medicine at the Georg-August University in G\u00f6ttingen and the Freie Universit\u00e4t Berlin, following which, he worked as an intensive care physician at the Charit\u00e9 Universit\u00e4tsmedizin. In 2001, he moved to the USA, working as a postdoctoral researcher at Boston University, then at UMass Chan Medical School, where he held his first professorship. In 2010, he returned to Germany and founded the Institute for Innate Immunity at the University Hospital Bonn. He became Scientific Director of the German Rheumatism Research Centre Berlin, a Leibniz Institute, and Professor of Experimental Rheumatology at the Charit\u00e9 Universit\u00e4tsmedizin Berlin in 2023. His research interests concern how the innate immune system maintains health and under what circumstances it can promote disease. In particular, he investigates the molecular mechanisms that lead to activation or inhibition of the immune system and how these influence the inflammatory reactions in various diseases, such as rheumatic diseases, arteriosclerosis or Alzheimer\u2019s disease.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Prof. Dr. Latz is spokesperson of the Collaborative Research Centre \u201cMetaflammation and Cellular Programming\u201d (SFB 1454) and was previously co-spokesperson of the Cluster of Excellence \u201cImmunoSensation\u00b2\u201d, both at the University of Bonn. He has also co-founded several biotech companies, including IFM Therapeutics (2017), Dioscure Therapeutics (2020), a \u2018Stealth\u2019 biotech\u2019 (2020), and Odyssey Therapeutics (2021), which translate his discoveries into novel therapeutics and preventive approaches. He has been a highly cited scientist in immunology since 2014 having published more than 300 publications. Prof. Dr. Latz was elected as a member of the German National Academy of Sciences (Leopoldina) in 2016 and has received a number of prestigious awards, including the Gottfried Wilhelm Leibniz Prize in 2018.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Weblinks:<\/strong><br>Google scholar (Eicke Latz)<br>ORCID (000-0003-1488-5666)<br>Highly Cited Researcher \u2013 2023 Clarivate\u2122<\/p>\n<\/section>\n\n\n\n  <section id=\"scientific-background\"\n           class=\"section accordion  alignwide  toc-item\"\n           data-open=\"multiple\">\n    <div class=\"container container--center container--medium\">\n              <h2 class=\"h3 section__heading launimation slideBottom\">Scientific Background<\/h2>\n      \n      \n      \n              <div id=\"panel-\"\n             class=\"accordion__category active\" role=\"tabpanel\"\n             aria-labelledby=\"tab-\">\n                    <script type=\"application\/ld+json\">\n            {\n              \"@context\": \"https:\/\/schema.org\",\n              \"@type\": \"FAQPage\",\n              \"mainEntity\": [{\"@type\": \"Question\",\"name\": \"Scientific Career - Previous Positions\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"2011 &#8211; 2023\nGroup leader, Innate Immunity in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany\n2006 \u2013 2013\nAssistant Professor of Medicine, Division of Infectious Diseases and Immunology, UMass Medical School, Worcester, MA, USA\n2003 \u2013 2006\nResearch Assistant Professor of Medicine, Division of Infectious Diseases and Immunology, UMass Medical School, Worcester, MA, USA\n2001 \u2013 2003\nPostdoctoral Fellow, Division of Infectious Diseases and Immunology, UMass Medical School, Worcester, MA, USA\n1999 \u2013 2001\nResearch Fellow, Molecular Sepsis Research Laboratories, Humboldt-University, Berlin, Germany\n1998 \u2013 2001\nInternship and Residency (Intensive Care), Department of Surgery, Charit\u00e9 University Hospital, Berlin, Germany\n1998\nVisiting Scientist, Department of Lipid Biochemistry, Merck Research Laboratories, Rahway, NJ, USA\"}},{\"@type\": \"Question\",\"name\": \"Education\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"2001\nDoctorate, Medicine (Dr. med.), Free University of Berlin, Berlin, Germany\n1998\nGerman Medical Licence Examination (State examination), License to practice Medicine (Approbation), Berlin, Germany\n1995 \u2013 2000\nUS Medical License Examinations I, II, III, Educational Commission for Foreign Medical Graduates, Philadelphia, USA\n1991 \u2013 1998\nStudies of Medicine, Georg-August-University G\u00f6ttingen and Free University of Berlin, Berlin, Germany\"}},{\"@type\": \"Question\",\"name\": \"Professional Activities\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"Since 2025\nMember of the Berlin Brandenburg Academy of Sciences\nSince 2025\nMember of the Advisory Board for Immunology &amp; Inflammation Berlin Symposium 2026\nSince 2025\nDeputy Chair of the Scientific Advisory Board &#8211; BIPS GmbH\nSince 2024\nMember, Innovation Board at Labor Berlin,\u00a0 Germany.\n2023 \u2013 date\nPortfolio Advisory Board (PAB) Member, IBT Lower Saxony, Germany\n2022 \u2013 date\nERC Panel Member, ERC starting grants, LS6 \u2013 Immunity, Infection and Immunotherapy\n2022 \u2013 date\nMentor, Creative Destruction Lab (CDL)-Berlin, European School of Management and Technology (ESMT) Berlin, Germany.\n2021 \u2013 2023\nElected Member, Supervisory Board of the University of Bonn (\u2018Hochschulrat\u2019)\n2021 \u2013 2023\nSpeaker, SFB 1454 \u201cMetaflammation and Cellular Programming\u201d, University of Bonn\n2018 \u2013 2023\nCo-Speaker, Cluster of Excellence \u201cImmunoSensation2\u201d, University of Bonn\n2016 \u2013 date\nMember, Helmholtz Think Tank, Helmholtz Society, Berlin\n2015 \u2013 2023\nChair of Scientific Advisory Board, MPI for Infection Biology, Berlin, Germany\n2008 \u2013 date\nConsultant (current and past): Novartis (Basel, Switzerland); Glaxo Smith Kline (London, UK); Medimmune (Gaithersburg, MD, USA); Biogen (Cambridge, MA, USA); Amgen (Seattle, WA, USA); Eisai Pharmaceuticals (Andover, MA, USA); Altana Pharmaceuticals (Konstanz, Germany); CBio Pharmaceuticals (Brisbane, Australia); Johnson &amp; Johnson (Brussels, Belgium); Boehringer (Ingelheim, Germany)\n2008 \u2013 2016\nMember of Therapeutic Area Scientific Advisory Panels (TASAP): Inflammation &amp; Immunology, Centers for Therapeutic Innovation, Pfizer (Cambridge, MA, USA)\n2010 \u2013 2023\nCommissions Head: BONFOR (intramural funding), Research Infrastructure; Commissions Member: Personnel &amp; Strategy, Finance, Core facilities; University of Bonn\n2005 \u2013 date\nMember of Advisory Boards (current and past): Pfizer Worldwide R &amp; D (New York, NY, USA); Gr\u00fcnenthal Pharmaceuticals (Aachen, Germany); Genzyme (Boston, MA, USA); Opsona Pharmaceuticals (Dublin, Ireland)\"}},{\"@type\": \"Question\",\"name\": \"Society Memberships\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"German Society for Immunology (DGFI), American Association of Immunologists (AAI), International Trained Immunity Consortium (INTRIM), Founding member.\"}},{\"@type\": \"Question\",\"name\": \"Fellowships and Awards\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"2023\nERC Advanced Research Grant\n2018\nGottfried-Wilhelm Leibniz-Prize\n2016\nElected Member, German National Academy of Sciences (Leopoldina)\n2014-2023\nyearly Highly Cited Researcher in Immunology, \u2018World\u2019s Most Influential Scientific Minds\u2019 (Thomson Reuters)\n2014\nKavli Fellow, United States National Academy of Sciences (NAS)\n2014\nERC Consolidator Grant\n2011\nGlaxo Smith Kline Clinical Science Award\n2009\nDana Foundation Award\n2004\nFOCIS Award\n2001\nDAAD Postdoctoral Grant\"}}]\n            }\n          <\/script>\n\n          <div class=\"accordion__content\">\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69db5b686457a_0\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Scientific Career &#8211; Previous Positions<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69db5b686457a_0\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>2011 &#8211; 2023<br \/>\nGroup leader, Innate Immunity in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany<\/p>\n<p>2006 \u2013 2013<br \/>\nAssistant Professor of Medicine, Division of Infectious Diseases and Immunology, UMass Medical School, Worcester, MA, USA<\/p>\n<p>2003 \u2013 2006<br \/>\nResearch Assistant Professor of Medicine, Division of Infectious Diseases and Immunology, UMass Medical School, Worcester, MA, USA<\/p>\n<p>2001 \u2013 2003<br \/>\nPostdoctoral Fellow, Division of Infectious Diseases and Immunology, UMass Medical School, Worcester, MA, USA<\/p>\n<p>1999 \u2013 2001<br \/>\nResearch Fellow, Molecular Sepsis Research Laboratories, Humboldt-University, Berlin, Germany<\/p>\n<p>1998 \u2013 2001<br \/>\nInternship and Residency (Intensive Care), Department of Surgery, Charit\u00e9 University Hospital, Berlin, Germany<\/p>\n<p>1998<br \/>\nVisiting Scientist, Department of Lipid Biochemistry, Merck Research Laboratories, Rahway, NJ, USA<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69db5b686457a_1\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Education<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69db5b686457a_1\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>2001<br \/>\nDoctorate, Medicine (Dr. med.), Free University of Berlin, Berlin, Germany<\/p>\n<p>1998<br \/>\nGerman Medical Licence Examination (State examination), License to practice Medicine (Approbation), Berlin, Germany<\/p>\n<p>1995 \u2013 2000<br \/>\nUS Medical License Examinations I, II, III, Educational Commission for Foreign Medical Graduates, Philadelphia, USA<\/p>\n<p>1991 \u2013 1998<br \/>\nStudies of Medicine, Georg-August-University G\u00f6ttingen and Free University of Berlin, Berlin, Germany<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69db5b686457a_2\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Professional Activities<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69db5b686457a_2\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>Since 2025<br \/>\nMember of the Berlin Brandenburg Academy of Sciences<\/p>\n<p>Since 2025<br \/>\nMember of the Advisory Board for Immunology &amp; Inflammation Berlin Symposium 2026<\/p>\n<p>Since 2025<br \/>\nDeputy Chair of the Scientific Advisory Board &#8211; BIPS GmbH<\/p>\n<p>Since 2024<br \/>\nMember, Innovation Board at Labor Berlin,\u00a0 Germany.<\/p>\n<p>2023 \u2013 date<br \/>\nPortfolio Advisory Board (PAB) Member, IBT Lower Saxony, Germany<\/p>\n<p>2022 \u2013 date<br \/>\nERC Panel Member, ERC starting grants, LS6 \u2013 Immunity, Infection and Immunotherapy<\/p>\n<p>2022 \u2013 date<br \/>\nMentor, Creative Destruction Lab (CDL)-Berlin, European School of Management and Technology (ESMT) Berlin, Germany.<\/p>\n<p>2021 \u2013 2023<br \/>\nElected Member, Supervisory Board of the University of Bonn (\u2018Hochschulrat\u2019)<\/p>\n<p>2021 \u2013 2023<br \/>\nSpeaker, SFB 1454 \u201cMetaflammation and Cellular Programming\u201d, University of Bonn<\/p>\n<p>2018 \u2013 2023<br \/>\nCo-Speaker, Cluster of Excellence \u201cImmunoSensation2\u201d, University of Bonn<\/p>\n<p>2016 \u2013 date<br \/>\nMember, Helmholtz Think Tank, Helmholtz Society, Berlin<\/p>\n<p>2015 \u2013 2023<br \/>\nChair of Scientific Advisory Board, MPI for Infection Biology, Berlin, Germany<\/p>\n<p>2008 \u2013 date<br \/>\nConsultant (current and past): Novartis (Basel, Switzerland); Glaxo Smith Kline (London, UK); Medimmune (Gaithersburg, MD, USA); Biogen (Cambridge, MA, USA); Amgen (Seattle, WA, USA); Eisai Pharmaceuticals (Andover, MA, USA); Altana Pharmaceuticals (Konstanz, Germany); CBio Pharmaceuticals (Brisbane, Australia); Johnson &amp; Johnson (Brussels, Belgium); Boehringer (Ingelheim, Germany)<\/p>\n<p>2008 \u2013 2016<br \/>\nMember of Therapeutic Area Scientific Advisory Panels (TASAP): Inflammation &amp; Immunology, Centers for Therapeutic Innovation, Pfizer (Cambridge, MA, USA)<\/p>\n<p>2010 \u2013 2023<br \/>\nCommissions Head: BONFOR (intramural funding), Research Infrastructure; Commissions Member: Personnel &amp; Strategy, Finance, Core facilities; University of Bonn<\/p>\n<p>2005 \u2013 date<br \/>\nMember of Advisory Boards (current and past): Pfizer Worldwide R &amp; D (New York, NY, USA); Gr\u00fcnenthal Pharmaceuticals (Aachen, Germany); Genzyme (Boston, MA, USA); Opsona Pharmaceuticals (Dublin, Ireland)<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69db5b686457a_3\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Society Memberships<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69db5b686457a_3\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>German Society for Immunology (DGFI), American Association of Immunologists (AAI), International Trained Immunity Consortium (INTRIM), Founding member.<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69db5b686457a_4\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Fellowships and Awards<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69db5b686457a_4\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>2023<br \/>\nERC Advanced Research Grant<\/p>\n<p>2018<br \/>\nGottfried-Wilhelm Leibniz-Prize<\/p>\n<p>2016<br \/>\nElected Member, German National Academy of Sciences (Leopoldina)<\/p>\n<p>2014-2023<br \/>\nyearly Highly Cited Researcher in Immunology, \u2018World\u2019s Most Influential Scientific Minds\u2019 (Thomson Reuters)<\/p>\n<p>2014<br \/>\nKavli Fellow, United States National Academy of Sciences (NAS)<\/p>\n<p>2014<br \/>\nERC Consolidator Grant<\/p>\n<p>2011<br \/>\nGlaxo Smith Kline Clinical Science Award<\/p>\n<p>2009<br \/>\nDana Foundation Award<\/p>\n<p>2004<br \/>\nFOCIS Award<\/p>\n<p>2001<br \/>\nDAAD Postdoctoral Grant<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                      <\/div>\n        <\/div>\n          <\/div>\n  <\/section>\n\n\n\n\n  <section id=\"top-5-publications\" class=\"section links-list  alignwide  toc-item\">\n    <div class=\"container container--center\">\n                        <h2 class=\"section__heading launimation slideBottom\">TOP 5 PUBLICATIONS<\/h2>\n        \n              \n      <div class=\"links-list__items-wrap\">\n        \n<div class=\"links-list__items links-list__items--row \">\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/s41590-023-01451-y\" target=\"_blank\" class=\"h6 links-list__item-title\">Mitochondrial damage activates the NLRP10 inflammasome<\/a>\n\n              <span class=\"links-list__item-underline\">Pr\u00f3chnicki T, Vasconcelos MB, Robinson KS, Mangan MSJ, De Graaf D, Shkarina K, Lovotti M, Standke L, Kaiser R, Stahl R, Duthie FG, Rothe M, Antonova K, Jenster LM, Lau ZH, R\u00f6sing S, Mirza N, Gott-schild C, Wachten D, G\u00fcnther C, Kufer TA, Schmidt FI, Zhong FL, Latz E. Mitochondrial damage activ-ates the NLRP10 inflammasome. Nat Immunol. 2023 Apr;24(4):595-603.<\/span>\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/s41590-023-01451-y\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.cell.com\/immunity\/fulltext\/S1074-7613(19)30490-X\" target=\"_blank\" class=\"h6 links-list__item-title\">Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase<\/a>\n\n              <span class=\"links-list__item-underline\">Mario A Lauterbach, Jasmin E Hanke, Magdalini Serefidou, Matthew SJ Mangan, Carl-Christian Kolbe, Timo Hess, Maximilian Rothe, Romina Kaiser, Florian Hoss, Jan Gehlen, Gudrun Engels, Maike Kreutzenbeck, Susanne V Schmidt, Anette Christ, Axel Imhof, Karsten Hiller, Eicke Latz. Toll-like re-ceptor signaling rewires macrophage metabolism and promotes histone acetylation via ATP-citrate lyase. Immunity. 2019 Dec 17; 51:6:997-1911<\/span>\n      \n      <a href=\"https:\/\/www.cell.com\/immunity\/fulltext\/S1074-7613(19)30490-X\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(17)31493-9?origin=app\" target=\"_blank\" class=\"h6 links-list__item-title\">Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming<\/a>\n\n              <span class=\"links-list__item-underline\">Christ A, G\u00fcnther P, Lauterbach MAR, Duewell P, Biswas D, Pelka K, Scholz CJ, Oosting M, Haendler K, Ba\u00dfler K, Klee K, Schulte-Schrepping J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E. Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell. 2018 Jan 11;172(1-2):162-175.e14<\/span>\n      \n      <a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(17)31493-9?origin=app\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/nature08938\" target=\"_blank\" class=\"h6 links-list__item-title\">NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals<\/a>\n\n              <span class=\"links-list__item-underline\">Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nunez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E (2010). NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 464: 1357-61<\/span>\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/nature08938\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/ni.1631\" target=\"_blank\" class=\"h6 links-list__item-title\">Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization<\/a>\n\n              <span class=\"links-list__item-underline\">Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E (2008). Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 9: 847-56<\/span>\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/ni.1631\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n  <\/div>\n      <\/div>\n    <\/div>\n  <\/section>\n\n\n\n\n  <section id=\"immunobiologie-der-entzuendung\" class=\"section cta  alignwide toc-item\">\n    <div class=\"container container--center\">\n\n      <div class=\"cta__wrapper bg bg--surface\">\n        <div class=\"cta__content\">\n                      <h2 class=\"cta__heading launimation slideBottom\">Immunobiologie der Entzu\u0308ndung<\/h2>\n          \n                      <div class=\"cta__desc wysiwyg launimation slideBottom\">AG Latz<\/div>\n          \n          \n                      <div class=\"cta__ctas button-group\">\n              <a href=\"\/arbeitsgruppen\/immunbiologie-der-entzuendung\/\" class=\"cta__button button button--arrow 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class=\"swiper-wrapper grid graded-boxes\">\n                          <div class=\"swiper-slide\">\n                \n<article\n  id=\"post-19726\" class=\"teaser-post box box--min-height launimation slideBottom graded-box post-19726 post type-post status-publish format-standard has-post-thumbnail hentry category-for-patients category-news-en tag-eicke-latz-en tag-kallinich tag-latz tag-mashreghi-en tag-program-area-1 tag-program-area-3 programme-area-tax-programme-area-1 programme-area-tax-programme-area-3 working-group-tax-chronic-inflammation-in-childhood working-group-tax-immunobiology-of-inflammation working-group-tax-therapeutic-gene-regulation\">\n  <div class=\"teaser-post__wrap\">\n    <div class=\"teaser-post__cats\">\n      \n<ul class=\"tag-pills tag-pills--small\" role=\"none\">\n      <li role=\"none\">\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        For patients      <\/span>\n    <\/li>\n  <\/ul>    <\/div>\n\n    <div class=\"teaser-post__body\">\n      <time class=\"date\" datetime=\"2025-09-29 08:55:20\">29.09.2025<\/time>\n      <div class=\"teaser-post__title h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/neuigkeiten\/three-drfz-researchers-as-the-top-100-minds-in-science-at-the-capital-in-2025\/\" aria-describedby=\"post-19726\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          Three DRFZ researchers as the top 100 minds in science at the capital in 2025        <\/a>\n      <\/div>\n\n              <div class=\"teaser-post__excerpt ellipsis\">\n          Tilmann Kallinich, Eicke Latz, and Mir-Farzin Mashreghi were selected by the Tagesspiegel Prof. Dr. Tilmann Kallinich, Prof. Dr. Eicke Latz, and PD Dr. Mir-Farzin Mashreghi\u2026        <\/div>\n          <\/div>\n  <\/div>\n<\/article>              <\/div>\n                          <div class=\"swiper-slide\">\n                \n<article\n  id=\"post-19391\" class=\"teaser-post box box--min-height launimation slideBottom graded-box post-19391 post type-post status-publish format-standard has-post-thumbnail hentry category-news-en category-publications tag-latz tag-program-area-1 programme-area-tax-programme-area-1 working-group-tax-immunobiology-of-inflammation\">\n  <div class=\"teaser-post__wrap\">\n    <div class=\"teaser-post__cats\">\n      \n<ul class=\"tag-pills tag-pills--small\" role=\"none\">\n      <li role=\"none\">\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        News      <\/span>\n    <\/li>\n  <\/ul>    <\/div>\n\n    <div class=\"teaser-post__body\">\n      <time class=\"date\" datetime=\"2025-08-26 07:58:24\">26.08.2025<\/time>\n      <div class=\"teaser-post__title h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/neuigkeiten\/nlrp3-as-a-driver-of-inflammation-in-common-diseases\/\" aria-describedby=\"post-19391\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          NLRP3 as a driver of inflammation in common diseases        <\/a>\n      <\/div>\n\n              <div class=\"teaser-post__excerpt ellipsis\">\n          Review about the key mediator of Arteriosklerose, Alzheimer und Gicht Prof. Dr. Eicke Latz, Scientific Director of the German Rheumatology Research Center, a Leibniz-Institute, together\u2026        <\/div>\n          <\/div>\n  <\/div>\n<\/article>              <\/div>\n                          <div class=\"swiper-slide\">\n                \n<article\n  id=\"post-18098\" class=\"teaser-post box box--min-height launimation slideBottom graded-box post-18098 post type-post status-publish format-standard hentry category-news-en tag-eicke-latz-en tag-immunobiology-of-inflammation tag-latz working-group-tax-immunobiology-of-inflammation\">\n  <div class=\"teaser-post__wrap\">\n    <div class=\"teaser-post__cats\">\n      \n<ul class=\"tag-pills tag-pills--small\" role=\"none\">\n      <li role=\"none\">\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        News      <\/span>\n    <\/li>\n  <\/ul>    <\/div>\n\n    <div class=\"teaser-post__body\">\n      <time class=\"date\" datetime=\"2025-06-19 07:17:09\">19.06.2025<\/time>\n      <div class=\"teaser-post__title h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/neuigkeiten\/eicke-latz-is-a-new-bbaw-member\/\" aria-describedby=\"post-18098\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          Eicke Latz is a new BBAW member        <\/a>\n      <\/div>\n\n              <div class=\"teaser-post__excerpt ellipsis\">\n          Prof. Dr. Eicke Latz, Scientific Director of the German Rheumatology Research Center, a Leibniz-Institute, has been welcomed as a full member of the Berlin-Brandenburg Academy\u2026        <\/div>\n          <\/div>\n  <\/div>\n<\/article>              <\/div>\n            \n          <\/div><!-- swiper-wrapper -->\n\n                      <div class=\"slider__pagination 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project type-project status-publish hentry programme-area-tax-programme-area-1 programme-area-tax-programme-area-2 programme-area-tax-programme-area-3 programme-area-tax-programme-area-4 programme-area-tax-technology-platforms-and-service-laboratories supporter-drfz-2 working-group-tax-b-cell-memory working-group-tax-immunobiology-of-inflammation\">\n  <div class=\"teaser-project__wrap\">\n          <div class=\"teaser-project__cats\">\n        \n<ul class=\"tag-pills tag-pills--small\" role=\"none\">\n      <li role=\"none\">\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        DRFZ      <\/span>\n    <\/li>\n  <\/ul>      <\/div>\n    \n    <div class=\"teaser-project__body\">\n      <div class=\"teaser-project__title h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/forschungsprojekte\/laboratory-network-rheumatology\/\" aria-describedby=\"post-20097\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          Laboratory 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Eicke Latz studied medicine at the Georg-August University in G\u00f6ttingen and the Freie Universit\u00e4t Berlin, following which, he worked as an\u2026<\/p>\n","protected":false},"author":1,"featured_media":1254,"menu_order":0,"template":"","department":[237,294],"function":[321],"liaison":[],"programme-area-function":[],"programme-area-tax":[179],"working-group-function":[521],"working-group-tax":[250],"class_list":["post-1685","head","type-head","status-publish","has-post-thumbnail","hentry","department-directors","department-pa-1-cell-and-tissue-rheumatology","function-scientific-director","programme-area-tax-programme-area-1","working-group-function-group-leader","working-group-tax-immunobiology-of-inflammation"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Prof. Dr. med. 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