{"id":3779,"date":"2025-01-21T14:08:56","date_gmt":"2025-01-21T14:08:56","guid":{"rendered":"https:\/\/www.drfz.de\/?post_type=head&#038;p=3779"},"modified":"2025-07-10T09:47:50","modified_gmt":"2025-07-10T09:47:50","slug":"ahmed-n-hegazy","status":"publish","type":"head","link":"https:\/\/www.drfz.de\/en\/koepfe\/ahmed-n-hegazy\/","title":{"rendered":"Prof. Dr. med. Dr. rer. nat. Ahmed N. Hegazy"},"content":{"rendered":"\n  <section id=\"scientific-background\"\n           class=\"section accordion  alignwide  toc-item\"\n           data-open=\"multiple\">\n    <div class=\"container container--center container--medium\">\n              <h2 class=\"h3 section__heading launimation slideBottom\">Scientific Background<\/h2>\n      \n      \n      \n              <div id=\"panel-\"\n             class=\"accordion__category active\" role=\"tabpanel\"\n             aria-labelledby=\"tab-\">\n                    <script type=\"application\/ld+json\">\n            {\n              \"@context\": \"https:\/\/schema.org\",\n              \"@type\": \"FAQPage\",\n              \"mainEntity\": [{\"@type\": \"Question\",\"name\": \"Scientific Career\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"Since 2023\nTenured W2 Professor of Translational Gastroenterology, Department of Gastroenterology, Infectious Diseases and Rheumatology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin\n2018 \u2013 2023\nLichtenberg Professor of Translational Gastroenterology, Department of Gastroenterology, Infectious Diseases and Rheumatology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin\nSince 2018\nPrincipal Investigator, German Rheumatism Research Centre Berlin\nSince 2017\nInternal Medicine Resident, Department of Gastroenterology, Infectiology and Rheumatology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany (Headed by Prof. Britta Siegmund); Qualification for \u201cFacharzt Innere Medizin\u201d\n2012 \u2013 2017\nPostdoctoral Researcher, Translational Gastroenterology Unit, Kennedy Institute of Rheumatology, University of Oxford, United Kingdom (Mentor: Prof. Fiona Powrie)\n2012 \u2013 2012\nResearch Associate, Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin (Headed by Prof. Max L\u00f6hning)\n2010 \u2013 2012\nInternal Medicine Resident, Department of Gastroenterology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany (Headed by Prof. Martin Zeitz)\n2006 \u2013 2007\nResearch Residence as part of Ph.D. training at the Institute of Experimental Immunology, University Hospital Z\u00fcrich, Switzerland (Mentors: Prof. Zinkernagel and Prof. H. Hengartner)\"}},{\"@type\": \"Question\",\"name\": \"Education\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"2012\nDoctor of Philosophy in Immunology (Dr. rer. nat.), \u201csumma cum laude\u201d; Institute of Biology, Humboldt University of Berlin, Germany; Dissertation: \u201eStability and Plasticity of T Helper Type 1 and Type 2 Differentiation Programs\u201c\n2010\nDoctor of Medicine (Dr. med.), \u201csumma cum laude\u201d, Department of Pediatric Hematology and Oncology, Hannover Medical School (MHH), Germany; Dissertation: \u201eRole of CD4+ T Cell-Mediated Anti-Tumor Immunity in a BCR-ABL+ Murine Model of Acute Lymphoblastic Leukemia\u201c\n2007\nApprobation, License to Practice Medicine, Germany\n2005\nStaatsexamen, Hannover Medical School, Germany\n1996 \u2013 2004\nBachelor of Medicine, Hannover Medical School (MHH), Germany and Faculty of Medicine, Cairo University, Egypt\"}},{\"@type\": \"Question\",\"name\": \"Society Membership\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"Deutsche Gesellschaft f\u00fcr Immunologie; British Society for Immunology; Deutsche Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten; European Crohn\u2019s &amp; Colitis Organisation; Arab-German Young Academy of sciences and humanities\"}},{\"@type\": \"Question\",\"name\": \"Fellowship and Awards\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"2023\nSuccessful evaluation of the Lichtenberg Professorship, Volkswagen Foundation\n2022\nAward of ERC Starting Grant 2022 \u201ciMOTIONS\u201d \u2013 European Commission\n2018\nFellow of the BIH Clinician Scientist Excellence Programme, BIH\n2017\nRobert-Koch Postdoctoral Prize in Immunology, RKI Foundation\n2017\nElection to the Arab-German Young Academy of Sciences and Humanities, Berlin &#8211; Brandenburg Academy of Sciences and Humanities\n2017\nFellow of the BIH Junior Clinician Scientist Programme, Berlin Institute of Health (BIH)\n2017\nLichtenberg Professorship, Volkswagen Foundation\n2014 &#8211; 2016\nMarie Curie Actions-Intra-European Fellowship for career development, European Commission\n2013 &#8211; 2014\nEMBO Long-Term Fellowship for postdoctoral research\n2012\nFeodor Lynen Research Fellowship, Alexander von Humboldt Foundation\n2011\nDissertation Award for Tumour Research, Hannover Medical School\"}}]\n            }\n          <\/script>\n\n          <div class=\"accordion__content\">\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69eca83386451_0\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Scientific Career<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69eca83386451_0\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>Since 2023<br \/>\nTenured W2 Professor of Translational Gastroenterology, Department of Gastroenterology, Infectious Diseases and Rheumatology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin<\/p>\n<p>2018 \u2013 2023<br \/>\nLichtenberg Professor of Translational Gastroenterology, Department of Gastroenterology, Infectious Diseases and Rheumatology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin<\/p>\n<p>Since 2018<br \/>\nPrincipal Investigator, German Rheumatism Research Centre Berlin<\/p>\n<p>Since 2017<br \/>\nInternal Medicine Resident, Department of Gastroenterology, Infectiology and Rheumatology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany (Headed by Prof. Britta Siegmund); Qualification for \u201cFacharzt Innere Medizin\u201d<\/p>\n<p>2012 \u2013 2017<br \/>\nPostdoctoral Researcher, Translational Gastroenterology Unit, Kennedy Institute of Rheumatology, University of Oxford, United Kingdom (Mentor: Prof. Fiona Powrie)<\/p>\n<p>2012 \u2013 2012<br \/>\nResearch Associate, Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin (Headed by Prof. Max L\u00f6hning)<\/p>\n<p>2010 \u2013 2012<br \/>\nInternal Medicine Resident, Department of Gastroenterology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany (Headed by Prof. Martin Zeitz)<\/p>\n<p>2006 \u2013 2007<br \/>\nResearch Residence as part of Ph.D. training at the Institute of Experimental Immunology, University Hospital Z\u00fcrich, Switzerland (Mentors: Prof. Zinkernagel and Prof. H. Hengartner)<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69eca83386451_1\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Education<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69eca83386451_1\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>2012<br \/>\nDoctor of Philosophy in Immunology (Dr. rer. nat.), \u201csumma cum laude\u201d; Institute of Biology, Humboldt University of Berlin, Germany; Dissertation: \u201eStability and Plasticity of T Helper Type 1 and Type 2 Differentiation Programs\u201c<\/p>\n<p>2010<br \/>\nDoctor of Medicine (Dr. med.), \u201csumma cum laude\u201d, Department of Pediatric Hematology and Oncology, Hannover Medical School (MHH), Germany; Dissertation: \u201eRole of CD4+ T Cell-Mediated Anti-Tumor Immunity in a BCR-ABL+ Murine Model of Acute Lymphoblastic Leukemia\u201c<\/p>\n<p>2007<br \/>\nApprobation, License to Practice Medicine, Germany<\/p>\n<p>2005<br \/>\nStaatsexamen, Hannover Medical School, Germany<\/p>\n<p>1996 \u2013 2004<br \/>\nBachelor of Medicine, Hannover Medical School (MHH), Germany and Faculty of Medicine, Cairo University, Egypt<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69eca83386451_2\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Society Membership<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69eca83386451_2\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p class=\"CV01Introduction\"><span>Deutsche Gesellschaft f\u00fcr Immunologie; British Society for Immunology; Deutsche Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten; European Crohn\u2019s &amp; Colitis Organisation; Arab-German Young Academy of sciences and humanities<\/span><\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69eca83386451_3\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Fellowship and Awards<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69eca83386451_3\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>2023<br \/>\nSuccessful evaluation of the Lichtenberg Professorship, Volkswagen Foundation<\/p>\n<p>2022<br \/>\nAward of ERC Starting Grant 2022 \u201ciMOTIONS\u201d \u2013 European Commission<\/p>\n<p>2018<br \/>\nFellow of the BIH Clinician Scientist Excellence Programme, BIH<\/p>\n<p>2017<br \/>\nRobert-Koch Postdoctoral Prize in Immunology, RKI Foundation<\/p>\n<p>2017<br \/>\nElection to the Arab-German Young Academy of Sciences and Humanities, Berlin &#8211; Brandenburg Academy of Sciences and Humanities<\/p>\n<p>2017<br \/>\nFellow of the BIH Junior Clinician Scientist Programme, Berlin Institute of Health (BIH)<\/p>\n<p>2017<br \/>\nLichtenberg Professorship, Volkswagen Foundation<\/p>\n<p>2014 &#8211; 2016<br \/>\nMarie Curie Actions-Intra-European Fellowship for career development, European Commission<\/p>\n<p>2013 &#8211; 2014<br \/>\nEMBO Long-Term Fellowship for postdoctoral research<\/p>\n<p>2012<br \/>\nFeodor Lynen Research Fellowship, Alexander von Humboldt Foundation<\/p>\n<p>2011<br \/>\nDissertation Award for Tumour Research, Hannover Medical School<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                      <\/div>\n        <\/div>\n          <\/div>\n  <\/section>\n\n\n\n\n  <section id=\"top-publications\" class=\"section links-list  alignwide  toc-item\">\n    <div class=\"container container--center\">\n                        <h2 class=\"section__heading launimation slideBottom\">TOP PUBLICATIONS<\/h2>\n        \n              \n      <div class=\"links-list__items-wrap\">\n        \n<div class=\"links-list__items links-list__items--row \">\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/s41590-025-02149-z\" target=\"_self\" class=\"h6 links-list__item-title\">The IL-22\u2013oncostatin M axis promotes intestinal inflammation and tumorigenesis<\/a>\n\n              <span class=\"links-list__item-underline\">Cineus R, Luo Y, Saliutina M, Manna S, Cancino CA, Velasco Bl\u00e1zquez L, Wang L, B\u00f6sel D, Abdelrahman A, Klementowicz JE, Scherl A, Hainbuch S, Br\u00e9art B, Kwon G, Konopka A, Guerra GM, von Coburg E, Gerbeth L, Roels J, Heinrich F, M\u00fcller N, Durek P, Deigendesch N, Ziai J, Hung J, Conrad T; TRR241 IBDome Consortium; K\u00fchl AA, Wirtz S, L\u00f6hning M, Keir M, Diefenbach A, Mashreghi MF, Siegmund B, Schumann M, Romagnani C, West NR, Hegazy AN. The IL-22-oncostatin M axis promotes intestinal inflammation and tumorigenesis. Nat Immunol. 2025 May 30. doi: 10.1038\/s41590-025-02149-z. Epub ahead of print. PMID: 40447860.<\/span>\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/s41590-025-02149-z\" target=\"_self\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2023.10.01.560386v1\" target=\"_blank\" class=\"h6 links-list__item-title\">Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4+ T cells as predictors for response to integrin \u03b14\u03b27-blocking therapy in patients with inflammatory bowel disease<\/a>\n\n              <span class=\"links-list__item-underline\">Horn, V., Cancino, C., Steinheuer, L., Fritz, K., Obermeyer-Wasserscheid, B., B\u00f6sel, D., Burns, M., Schulz, A., Mantzivi, E., Sonnenberg, E., Weidinger, C., Siegmund, B., Mei, H. E., Thurley, K., &amp; Hegazy, A. N. (2023). Multi-omic approach identifies circulating T cell characteristics associated with response to anti-integrin biologic therapy in inflammatory bowel diseases. *Biorxiv*. https:\/\/doi.org\/10.1101\/2023.10.01.560386<\/span>\n      \n      <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2023.10.01.560386v1\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/doi.org\/10.1126\/sciadv.adk2693\" target=\"_self\" class=\"h6 links-list__item-title\">Plasticity and lineage commitment of individual Th1 cells are determined by stable T-bet expression quantities. Sci Adv. 2024 Jun 7;10(23)<\/a>\n\n              <span class=\"links-list__item-underline\">Hegazy, A.N., Peine, C., Niesen, D., Panse, I., Vainshtein, Y., Kommer, C., Zhang, Q, Brunner, T.M., Peine, M., Fr\u00f6hlich, A., Ishaque, N., Marek, R.M., Zhu, J., H\u00f6fer, T., L\u00f6hning, M. (2024). Plasticity and lineage commitment of individual Th1 cells are determined by stable T-bet expression quantities. Sci Adv. 2024 Jun 7;10(23):eadk2693<\/span>\n      \n      <a href=\"https:\/\/doi.org\/10.1126\/sciadv.adk2693\" target=\"_self\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.gastrojournal.org\/article\/S0016-5085(17)35979-6\/fulltext\" target=\"_blank\" class=\"h6 links-list__item-title\">Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation<\/a>\n\n              <span class=\"links-list__item-underline\">Hegazy* , A. N., West*, N. R.,  et al., (2017). Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation. Gastroenterology 153, 1320-1337.e16. <\/span>\n      \n      <a href=\"https:\/\/www.gastrojournal.org\/article\/S0016-5085(17)35979-6\/fulltext\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/nm.4307\" target=\"_blank\" class=\"h6 links-list__item-title\">Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor\u2013neutralizing therapy in patients with inflammatory bowel disease<\/a>\n\n              <span class=\"links-list__item-underline\">West* , N. R., Hegazy* , A. N., et al., (2017). Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease. Nat Med 23, 579\u2013589. <\/span>\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/nm.4307\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.cell.com\/immunity\/fulltext\/S1074-7613(15)00438-0?innerTabvideo-abstract_mmc5=\" target=\"_blank\" class=\"h6 links-list__item-title\">Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage<\/a>\n\n              <span class=\"links-list__item-underline\">Bhattacharya* , A., Hegazy *, A.N., et al., (2015). Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage. Immunity 43, 974\u2013986. <\/span>\n      \n      <a href=\"https:\/\/www.cell.com\/immunity\/fulltext\/S1074-7613(15)00438-0?innerTabvideo-abstract_mmc5=\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.cell.com\/immunity\/fulltext\/S1074-7613(09)00548-2\" target=\"_blank\" class=\"h6 links-list__item-title\">Interferons Direct Th2 Cell Reprogramming to Generate a Stable GATA-3+T-bet+ Cell Subset with Combined Th2 and Th1 Cell Functions<\/a>\n\n              <span class=\"links-list__item-underline\">Hegazy, A.N., et al., (2010). Interferons Direct Th2 Cell Reprogramming to Generate a Stable GATA-3+T-bet+ Cell Subset with Combined Th2 and Th1 Cell Functions. Immunity 32, 116\u2013128.<\/span>\n      \n      <a href=\"https:\/\/www.cell.com\/immunity\/fulltext\/S1074-7613(09)00548-2\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n  <\/div>\n      <\/div>\n    <\/div>\n  <\/section>\n\n\n\n\n  <section id=\"inflammatory-mechanisms\" class=\"section cta  alignwide toc-item\">\n    <div class=\"container container--center\">\n\n      <div class=\"cta__wrapper bg bg--surface\">\n        <div class=\"cta__content\">\n                      <h2 class=\"cta__heading launimation slideBottom\">Inflammatory Mechanisms<\/h2>\n          \n                      <div class=\"cta__desc wysiwyg launimation slideBottom\">Hegazy lab<\/div>\n          \n          \n                      <div class=\"cta__ctas button-group\">\n              <a href=\"\/en\/arbeitsgruppen\/entzundungsmechanismen\/\" class=\"cta__button button button--arrow launimation slideBottom\" title=\"learn more\" target=\"_blank\"><span>learn more<\/span><\/a>            <\/div>\n                  <\/div><!-- content -->\n\n                  <div class=\"cta__image launimation fadeIn\">\n            <img decoding=\"async\" loading=\"lazy\" sizes=\"auto, \" src=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/01\/Hegayz-group-150x66.jpg\" data-src=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/01\/Hegayz-group-1024x448.jpg\" data-srcset=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/01\/Hegayz-group.jpg 1920w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/01\/Hegayz-group.jpg 1600w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/01\/Hegayz-group-1366x598.jpg 1366w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/01\/Hegayz-group-1024x448.jpg 1024w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/01\/Hegayz-group-768x336.jpg 768w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/01\/Hegayz-group-550x241.jpg 550w\" class=\"\" 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class=\"swiper-wrapper grid graded-boxes\">\n                          <div class=\"swiper-slide\">\n                \n<article\n  id=\"post-17702\" class=\"teaser-post box box--min-height launimation slideBottom graded-box post-17702 post type-post status-publish format-standard has-post-thumbnail hentry category-news-en category-publications tag-hegazy_en tag-inflammatory-mechanisms-en tag-inflammatory-mechanisms tag-program-area-4 working-group-tax-inflammatory-mechanisms\">\n  <div class=\"teaser-post__wrap\">\n    <div class=\"teaser-post__cats\">\n      \n<ul class=\"tag-pills tag-pills--small\" role=\"none\">\n      <li role=\"none\">\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        News      <\/span>\n    <\/li>\n  <\/ul>    <\/div>\n\n    <div class=\"teaser-post__body\">\n      <time class=\"date\" datetime=\"2025-05-30 12:20:17\">30.05.2025<\/time>\n      <div class=\"teaser-post__title h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/neuigkeiten\/new-inflammatory-mechanism-discovered-in-chronic-intestinal-inflammation\/\" aria-describedby=\"post-17702\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          New inflammatory mechanism discovered in chronic intestinal inflammation        <\/a>\n      <\/div>\n\n              <div class=\"teaser-post__excerpt ellipsis\">\n          Oncostatin M as a key target for therapies Chronic inflammatory bowel diseases such as Crohn&#8217;s disease and ulcerative colitis are difficult to treat and are\u2026        <\/div>\n          <\/div>\n  <\/div>\n<\/article>              <\/div>\n                          <div class=\"swiper-slide\">\n                \n<article\n  id=\"post-17475\" class=\"teaser-post box box--min-height launimation slideBottom graded-box post-17475 post type-post status-publish format-standard hentry category-for-patients category-news-en tag-clinical-rheumatology tag-developmental-mucosal-immunology tag-immunobiology-of-inflammation tag-inflammatory-mechanisms tag-innate-immunity tag-macrophages-in-chronic-inflammation tag-program-area-1 tag-program-area-4 working-group-tax-clinical-rheumatology working-group-tax-developmental-and-mucosal-immunology working-group-tax-immunobiology-of-inflammation working-group-tax-inflammatory-mechanisms working-group-tax-innate-immunity working-group-tax-macrophage-biology-and-innate-cellular-networks-in-chronic-inflammatory-diseases\">\n  <div class=\"teaser-post__wrap\">\n    <div class=\"teaser-post__cats\">\n      \n<ul class=\"tag-pills tag-pills--small\" role=\"none\">\n      <li role=\"none\">\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        For patients      <\/span>\n    <\/li>\n  <\/ul>    <\/div>\n\n    <div class=\"teaser-post__body\">\n      <time class=\"date\" datetime=\"2025-05-22 15:56:22\">22.05.2025<\/time>\n      <div class=\"teaser-post__title h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/neuigkeiten\/early-recognition-targeted-intervention-staying-healthy-immunoprecept-unites-top-berlin-research\/\" aria-describedby=\"post-17475\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          Early recognition, targeted intervention, staying healthy: ImmunoPreCept unites top Berlin research        <\/a>\n      <\/div>\n\n              <div class=\"teaser-post__excerpt ellipsis\">\n          The DRFZ is part of the new Cluster of Excellence The German Rheumatology Research Center, a Leibniz Institute, is partner in the new Berlin Cluster\u2026        <\/div>\n          <\/div>\n  <\/div>\n<\/article>              <\/div>\n                          <div class=\"swiper-slide\">\n                \n<article\n  id=\"post-8328\" class=\"teaser-post box box--min-height launimation slideBottom graded-box post-8328 post type-post status-publish format-standard has-post-thumbnail hentry category-publications tag-ahmed-hegazy-en-en tag-inflammatory-mechanisms tag-program-area-4 programme-area-tax-programme-area-4 working-group-tax-inflammatory-mechanisms\">\n  <div class=\"teaser-post__wrap\">\n    <div class=\"teaser-post__cats\">\n      \n<ul class=\"tag-pills tag-pills--small\" role=\"none\">\n      <li role=\"none\">\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        Publications      <\/span>\n    <\/li>\n  <\/ul>    <\/div>\n\n    <div class=\"teaser-post__body\">\n      <time class=\"date\" datetime=\"2024-11-08 10:11:00\">08.11.2024<\/time>\n      <div class=\"teaser-post__title h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/neuigkeiten\/biomarker-fuer-therapieerfolg-bei-chronischen-darmentzuendungen-identifiziert\/\" aria-describedby=\"post-8328\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          Biomarker identified that predicts therapeutic success in chronic inflammatory bowel disease        <\/a>\n      <\/div>\n\n              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button launimation slideBottom\">Show more<\/a>\n<\/div>\n          <\/div>\n              <\/div>\n\n    <\/div><!-- container -->\n  <\/section>\n\n\n\n\n  <section id=\"projects\"\n           class=\"section related-projects alignwide related-projects--slider  toc-item\">\n    <div class=\"container container--center\">\n      <div class=\"related-projects__wrap\">\n                  <div class=\"section__heading-container launimation slideBottom\">\n                          <h2 class=\"section__heading\">Projects<\/h2>\n                                  <\/div>\n        \n        \n        <div class=\"related-projects__slider swiper swiper-pull-right\">\n                      <div class=\"slider__skip-links-container\">\n              <a id=\"before-slider-block_4568393fe139a3f186ef08d3e56c907b\"\n                 href=\"#after-slider-block_4568393fe139a3f186ef08d3e56c907b\"\n                 class=\"slider-skip-link\">Go to end of slider<\/a>\n            <\/div>\n          \n   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h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/forschungsprojekte\/cluster-of-excellence-immunoprecept\/\" aria-describedby=\"post-17506\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          Cluster of Excellence ImmunoPreCept        <\/a>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/article>              <\/div>\n                          <div class=\"swiper-slide\">\n                <article\n  id=\"post-4542\" class=\"teaser-project box launimation slideBottom graded-box post-4542 project type-project status-publish hentry programme-area-tax-programme-area-4 supporter-european-union working-group-tax-inflammatory-mechanisms\">\n  <div class=\"teaser-project__wrap\">\n          <div class=\"teaser-project__cats\">\n        \n<ul class=\"tag-pills tag-pills--small\" role=\"none\">\n      <li role=\"none\">\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        European Union      <\/span>\n    <\/li>\n  <\/ul>      <\/div>\n    \n    <div class=\"teaser-project__body\">\n      <div class=\"teaser-project__title h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/forschungsprojekte\/erc-starting-grant-imotions\/\" aria-describedby=\"post-4542\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          ERC starting grant: iMOTIONS        <\/a>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/article>              <\/div>\n                          <div class=\"swiper-slide\">\n                <article\n  id=\"post-4114\" class=\"teaser-project box launimation slideBottom graded-box post-4114 project type-project status-publish hentry programme-area-tax-programme-area-1 programme-area-tax-programme-area-3 programme-area-tax-programme-area-4 supporter-dfg-en working-group-tax-cell-biology working-group-tax-chronic-inflammation working-group-tax-developmental-and-mucosal-immunology working-group-tax-inflammatory-mechanisms working-group-tax-innate-immunity working-group-tax-macrophage-biology-and-innate-cellular-networks-in-chronic-inflammatory-diseases working-group-tax-schwiete-lab-for-microbiota-and-inflammation-en\">\n  <div class=\"teaser-project__wrap\">\n          <div class=\"teaser-project__cats\">\n        \n<ul class=\"tag-pills tag-pills--small\" role=\"none\">\n      <li role=\"none\">\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        DFG      <\/span>\n    <\/li>\n  <\/ul>      <\/div>\n    \n    <div class=\"teaser-project__body\">\n      <div class=\"teaser-project__title h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/forschungsprojekte\/dfg-sfb-trr-241\/\" aria-describedby=\"post-4114\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          DFG CRC TRR 241 &#8211; Immune-Epithelial Communication in Inflammatory Bowel Diseases        <\/a>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/article>              <\/div>\n            \n          <\/div><!-- 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","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":1374,"menu_order":0,"template":"","department":[295],"function":[],"liaison":[298],"programme-area-function":[],"programme-area-tax":[182],"working-group-function":[521],"working-group-tax":[246],"class_list":["post-3779","head","type-head","status-publish","has-post-thumbnail","hentry","department-pa-4-translational-rheumatology","liaison-charite-gastroenterology-infectiology-and-rheumatology","programme-area-tax-programme-area-4","working-group-function-group-leader","working-group-tax-inflammatory-mechanisms"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Prof. Dr. med. 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