{"id":3991,"date":"2025-01-07T11:11:46","date_gmt":"2025-01-07T11:11:46","guid":{"rendered":"https:\/\/www.drfz.de\/?post_type=head&#038;p=3991"},"modified":"2025-09-09T11:01:22","modified_gmt":"2025-09-09T11:01:22","slug":"mir-farzin-mashreghi","status":"publish","type":"head","link":"https:\/\/www.drfz.de\/en\/koepfe\/mir-farzin-mashreghi\/","title":{"rendered":"Dr. Mir-Farzin Mashreghi"},"content":{"rendered":"\n  <section id=\"scientific-background\"\n           class=\"section accordion  alignwide  toc-item\"\n           data-open=\"multiple\">\n    <div class=\"container container--center container--medium\">\n              <h2 class=\"h3 section__heading launimation slideBottom\">Scientific Background<\/h2>\n      \n      \n      \n              <div id=\"panel-\"\n             class=\"accordion__category active\" role=\"tabpanel\"\n             aria-labelledby=\"tab-\">\n                    <script type=\"application\/ld+json\">\n            {\n              \"@context\": \"https:\/\/schema.org\",\n              \"@type\": \"FAQPage\",\n              \"mainEntity\": [{\"@type\": \"Question\",\"name\": \"Scientific Career\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"Since 2023\nDeputy Scientific Director at DRFZ (since May 2023)\nSince 2022\nHead of the third Research Area \u201cSystems Rheumatology\u201d at the DRFZ (November 2022)\n2020-2022\nGroup Leader of the joint DRFZ\/BIH Center for Regenerative Therapies (B-CRT) \u201cSingle-Cell-Laboratory for Advanced Cellular Therapies\u201d.\nSince 2018\nScientific Head \u201cNext Generation Sequencing\u201d, Leader of the Laboratory of Molecular Rheumatology \u201cRegine von Ramin Labor\u201d at the DRFZ.\nSince 2016\nGroup Leader \u201cTherapeutic Gene Regulation\u201d, Programme Area III: Regenerative Rheumatology at the DRFZ Berlin.\n2007 \u20132016\nResearch Associate at the Cell Biology department (Head: Prof. Dr. Andreas Radbruch) at the DRFZ Berlin.\"}},{\"@type\": \"Question\",\"name\": \"Education\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"2025\nCompleted postdoctoral dissertation (Habilitation, prerequisite for professorship) at the Charit\u00e9 &#8211; University Medicine Berlin\n2024\nFachimmunologe der Deutschen Gesellschaft f\u00fcr Immunologie (DGFI)\n2003 \u20132007\nPhD thesis at the Charit\u00e9 Universit\u00e4tsmedizin Berlin, Institute of Medical Immunology, Supervisors: Prof. Dr. H.-D. Volk \/ Prof. Dr. P.-M. Kloetzel; \u201cFunctional analysis of the transcription factor STAT3 regulated by the induction of the cytoprotective enzyme heme oxygenase-1\u201d, magna cum laude\n2002 \u20132003\nDiploma thesis at the Charit\u00e9 Universit\u00e4tsmedizin Berlin, Institute of Medical Immunology, Supervisor, Prof. Dr. H.-D. Volk; \u201cStrategies for the diagnosis of subclinical and clinical acute rejection episodes in renal transplantation\u201d\n1998 \u20132003\nUniversity studies at the Freie Universit\u00e4t Berlin, Department of Biology, Pharmacy und Chemistry, Field: Biochemistry diploma, Subjects: Biochemistry, Biophysics, Immunology, Biology, Organic Chemistry, Physical Chemistry and Physics. Mark: Excellent\"}},{\"@type\": \"Question\",\"name\": \"Professional Activities\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"Since 2023\nDRFZ Lead PI, Area \u201cImmunity, Inflammation and Infection\u201d of the \u201eDeutsches Zentrum fu\u0308r Kinder und Jugendgesundheit\u201c, Berlin Location\n2018-2023\nStudy Group Coordinator of EFIS-IL-Study Group \u201cNon-coding RNA and epigenetic regulation in immune cells\u201d\"}},{\"@type\": \"Question\",\"name\": \"Society Memberships\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"Deutsche Gesellschaft f\u00fcr Immunologie (DGFI)\"}},{\"@type\": \"Question\",\"name\": \"Fellowships and Awards\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"Wolfgang Schulze Award 2011, \u201eTherapeutic use of microRNAs in rheumatology\u201c\"}}]\n            }\n          <\/script>\n\n          <div class=\"accordion__content\">\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69d4a04291a38_0\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Scientific Career<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69d4a04291a38_0\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>Since 2023<br \/>\nDeputy Scientific Director at DRFZ (since May 2023)<\/p>\n<p>Since 2022<br \/>\nHead of the third Research Area \u201cSystems Rheumatology\u201d at the DRFZ (November 2022)<\/p>\n<p>2020-2022<br \/>\nGroup Leader of the joint DRFZ\/BIH Center for Regenerative Therapies (B-CRT) \u201cSingle-Cell-Laboratory for Advanced Cellular Therapies\u201d.<\/p>\n<p>Since 2018<br \/>\nScientific Head \u201cNext Generation Sequencing\u201d, Leader of the Laboratory of Molecular Rheumatology \u201cRegine von Ramin Labor\u201d at the DRFZ.<\/p>\n<p>Since 2016<br \/>\nGroup Leader \u201cTherapeutic Gene Regulation\u201d, Programme Area III: Regenerative Rheumatology at the DRFZ Berlin.<\/p>\n<p>2007 \u20132016<br \/>\nResearch Associate at the Cell Biology department (Head: Prof. Dr. Andreas Radbruch) at the DRFZ Berlin.<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69d4a04291a38_1\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Education<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69d4a04291a38_1\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>2025<br \/>\nCompleted postdoctoral dissertation (Habilitation, prerequisite for professorship) at the Charit\u00e9 &#8211; University Medicine Berlin<\/p>\n<p>2024<br \/>\nFachimmunologe der Deutschen Gesellschaft f\u00fcr Immunologie (DGFI)<\/p>\n<p>2003 \u20132007<br \/>\nPhD thesis at the Charit\u00e9 Universit\u00e4tsmedizin Berlin, Institute of Medical Immunology, Supervisors: Prof. Dr. H.-D. Volk \/ Prof. Dr. P.-M. Kloetzel; \u201cFunctional analysis of the transcription factor STAT3 regulated by the induction of the cytoprotective enzyme heme oxygenase-1\u201d, magna cum laude<\/p>\n<p>2002 \u20132003<br \/>\nDiploma thesis at the Charit\u00e9 Universit\u00e4tsmedizin Berlin, Institute of Medical Immunology, Supervisor, Prof. Dr. H.-D. Volk; \u201cStrategies for the diagnosis of subclinical and clinical acute rejection episodes in renal transplantation\u201d<\/p>\n<p>1998 \u20132003<br \/>\nUniversity studies at the Freie Universit\u00e4t Berlin, Department of Biology, Pharmacy und Chemistry, Field: Biochemistry diploma, Subjects: Biochemistry, Biophysics, Immunology, Biology, Organic Chemistry, Physical Chemistry and Physics. Mark: Excellent<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69d4a04291a38_2\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Professional Activities<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69d4a04291a38_2\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>Since 2023<br \/>\nDRFZ Lead PI, Area \u201cImmunity, Inflammation and Infection\u201d of the \u201eDeutsches Zentrum fu\u0308r Kinder und Jugendgesundheit\u201c, Berlin Location<\/p>\n<p>2018-2023<br \/>\nStudy Group Coordinator of EFIS-IL-Study Group \u201cNon-coding RNA and epigenetic regulation in immune cells\u201d<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69d4a04291a38_3\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Society Memberships<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69d4a04291a38_3\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p class=\"CV01Introduction\">Deutsche Gesellschaft f\u00fcr Immunologie (DGFI)<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69d4a04291a38_4\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Fellowships and Awards<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69d4a04291a38_4\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>Wolfgang Schulze Award 2011, \u201eTherapeutic use of microRNAs in rheumatology\u201c<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                      <\/div>\n        <\/div>\n          <\/div>\n  <\/section>\n\n\n\n\n  <section id=\"top-5-publikationen-der-karriere\" class=\"section links-list  alignwide  toc-item\">\n    <div class=\"container container--center\">\n                        <h2 class=\"section__heading launimation slideBottom\">Top Publications<\/h2>\n        \n              \n      <div class=\"links-list__items-wrap\">\n        \n<div class=\"links-list__items links-list__items--row \">\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/s41586-025-08697-6\" target=\"_self\" class=\"h6 links-list__item-title\">TGF\u03b2 links EBV to multisystem inflammatory syndrome in children<\/a>\n\n              <span class=\"links-list__item-underline\">Goetzke CC, Massoud M, Frischbutter S, Guerra GM, Ferreira-Gomes M, Heinrich F, von Stuckrad ASL, Wisniewski S, Licha JR, Bondareva M, Ehlers L, Plassart SK, Javouhey E, Pons S, Trouillet-Assant S, Ozsurekci Y, Zhang Y, Poli MC, Discepolo V, Lo Vecchio A, Sahin B, Verboom M, Hallensleben M, Heuhsen AI, Astudillo C, Espinosa Y, Vial Cox MC, Dobbs K, Delmonte OM, Montealegre GA, Magliocco M, Barron K, Danielson J, Petrov L, Unterwalder N, Sawitzki B, Matz M, Lehmann K, Gratopp A, von Bernuth H, Burkhardt LM, Wiese N, Peter L, Schmueck-Henneresse M, Amini L, Maurer M, Roehmel JF, Gewurz BE, Yonker LM, Witkowski M, Kruglov A, Mall MA, Su HC, Ozen S, Radbruch A, Belot A, Durek P, Kallinich T, Mashreghi MF (2025). TGF\u03b2 links EBV to multisystem inflammatory syndrome in children. Nature, Epub ahead of print. https:\/\/www.nature.com\/articles\/s41586-025-08697-6<\/span>\n      \n      <a href=\"https:\/\/www.nature.com\/articles\/s41586-025-08697-6\" target=\"_self\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38755157\/\" target=\"_blank\" class=\"h6 links-list__item-title\">Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow<\/a>\n\n              <span class=\"links-list__item-underline\">Ferreira-Gomes M, Chen Y, Durek P, Rincon-Arevalo H, Heinrich F, Bauer L, Szelinski F, Guerra GM, Stefanski AL, Niedobitek A, Wiedemann A, Bondareva M, Ritter J, Lehmann K, Hardt S, Hipfl C, Hein S, Hildt E, Matz M, Mei HE, Cheng Q, Dang VD, Witkowski M, Lino AC, Kruglov A, Melchers F, Perka C, Schrezenmeier EV, Hutloff A, Radbruch A, D\u00f6rner T, Mashreghi MF. Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow. Nat Commun. 2024 May 17;15(1):4182. doi: 10.1038\/s41467-024-48570-0. PMID: 38755157; PMCID: PMC11099182.<\/span>\n      \n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38755157\/\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37386908\/\" target=\"_blank\" class=\"h6 links-list__item-title\">Serum TGF-\u03b2 as a predictive biomarker for severe disease and fatality of COVID-19<\/a>\n\n              <span class=\"links-list__item-underline\">Frischbutter S, Durek P, Witkowski M, Angermair S, Treskatsch S, Maurer M, Radbruch A, Mashreghi MF. Serum TGF-\u03b2 as a predictive biomarker for severe disease and fatality of COVID-19. Eur J Immunol. 2023 Oct;53(10):e2350433. doi:10.1002\/eji.202350433. Epub 2023 Jul 12. PMID: 37386908.<\/span>\n      \n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37386908\/\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37944493\/\" target=\"_blank\" class=\"h6 links-list__item-title\">Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry<\/a>\n\n              <span class=\"links-list__item-underline\">Bondareva M, Budzinski L, Durek P, Witkowski M, Angermair S, Ninnemann J, Kreye J, Letz P, Ferreira-Gomes M, Semin I, Guerra GM, Momsen Reincke S, S\u00e1nchez-Sendin E, Yilmaz S, Sempert T, Heinz GA, Tizian C, Raftery M, Sch\u00f6nrich G, Matyushkina D, Smirnov IV, Govorun VM, Schrezenmeier E, Stefanski AL, D\u00f6rner T, Zocche S, Viviano E, Klement N, Sehmsdorf KJ, Lunin A, Chang HD, Drutskaya M, Kozlovskaya L, Treskatsch S, Radbruch A, Diefenbach A, Pr\u00fcss H, Enghard P, Mashreghi MF*, Kruglov AA*. Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry. Cell Host Microbe. 2023 Nov 8;31(11):1866-1881.e10. doi: 10.1016\/j.chom.2023.10.007. PMID: 37944493. *equal contribution<\/span>\n      \n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37944493\/\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36228431\/\" target=\"_blank\" class=\"h6 links-list__item-title\">Induction of cross-reactive, mucosal anti-SARS-CoV-2 antibody responses in rheumatoid arthritis patients after 3rd dose of COVID-19 vaccination<\/a>\n\n              <span class=\"links-list__item-underline\">Bondareva M, Letz P, Karberg K, Schrezenmeier E, Semin I, Rincon-Arevalo H, D\u00f6rner T, Mashreghi MF, Stefanski AL, Kruglov AA. Induction of cross-reactive, mucosal anti-SARS-CoV-2 antibody responses in rheumatoid arthritis patients after 3rd dose of COVID-19 vaccination. J Autoimmun. 2022 Dec;133:102918. doi: 10.1016\/j.jaut.2022.102918. Epub 2022 Oct 11. PMID: 36228431; PMCID: PMC9550527.<\/span>\n      \n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36228431\/\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36204213\/\" target=\"_blank\" class=\"h6 links-list__item-title\">Human regulatory T cells locally differentiate and are functionally heterogeneous within the inflamed arthritic joint<\/a>\n\n              <span class=\"links-list__item-underline\">Lutter L, van der Wal MM, Brand EC, Maschmeyer P, Vastert S, Mashreghi MF, van Loosdregt J, van Wijk F. Human regulatory T cells locally differentiate and are functionally heterogeneous within the inflamed arthritic joint. Clin Transl Immunology. 2022 Sep 30;11(10):e1420. doi: 10.1002\/cti2.1420. PMID: 36204213;PMCID: PMC9525321.<\/span>\n      \n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36204213\/\" target=\"_blank\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/doi.org\/10.1038\/s41467-021-22210-3\" target=\"_self\" class=\"h6 links-list__item-title\">SARS-CoV-2 in severe COVID-19 induces a TGF-beta-dominated chronic immune response that does not target itself<\/a>\n\n              <span class=\"links-list__item-underline\">Ferreira-Gomes, M., Kruglov, A., Durek, P., Heinrich, F., Tizian, C., Heinz, G. A., Pascual-Reguant, A., Du, W., Mothes, R., Fan, C., Frischbutter, S., Habenicht, K., Budzinski, L., Ninnemann, J., Jani, P. K., Guerra, G. M., Lehmann, K., Matz, M., Ostendorf, L., Heiberger, L., Chang, H. D., . . . Mashreghi, M. F. (2021). SARS-CoV-2 in severe COVID-19 induces a TGF-beta-dominated chronic immune response that does not target itself. Nat Commun, 12(1), 1961. https:\/\/doi.org\/10.1038\/s41467-021-22210-3<\/span>\n      \n      <a href=\"https:\/\/doi.org\/10.1038\/s41467-021-22210-3\" target=\"_self\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n      <div class=\"links-list__item  launimation slideBottom\">\n      \n      <a href=\"https:\/\/doi.org\/10.1038\/ni.1945\" target=\"_self\" class=\"h6 links-list__item-title\">The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes<\/a>\n\n              <span class=\"links-list__item-underline\">Stittrich, A. B., Haftmann, C., Sgouroudis, E., Kuhl, A. A., Hegazy, A. N., Panse, I., Riedel, R., Flossdorf, M., Dong, J., Fuhrmann, F., Heinz, G. A., Fang, Z., Li, N., Bissels, U., Hatam, F., Jahn, A., Hammoud, B., Matz, M., Schulze, F. M.,  &#8230; Mashreghi, M. F. (2010). The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes. Nat Immunol, 11(11), 1057-1062. https:\/\/doi.org\/10.1038\/ni.1945<\/span>\n      \n      <a href=\"https:\/\/doi.org\/10.1038\/ni.1945\" target=\"_self\" class=\"links-list__item-link\">\n        <span class=\"button button--arrow button--arrow-nw button--arrow-link\" ><\/span>\n      <\/a>\n    <\/div>\n  <\/div>\n      <\/div>\n    <\/div>\n  <\/section>\n\n\n\n\n  <section id=\"mashreghi-lab\" class=\"section cta  alignwide toc-item\">\n    <div class=\"container container--center\">\n\n      <div class=\"cta__wrapper bg bg--surface\">\n        <div class=\"cta__content\">\n                      <h2 class=\"cta__heading launimation slideBottom\">Mashreghi lab<\/h2>\n          \n                      <div class=\"cta__desc wysiwyg launimation slideBottom\">With oligonucleotides against \u201ediseased\u201c cells<\/div>\n          \n          \n                      <div class=\"cta__ctas button-group\">\n              <a href=\"\/en\/arbeitsgruppen\/therapeutische-genregulation\/\" class=\"cta__button button button--arrow launimation slideBottom\" title=\"learn more\" target=\"_blank\"><span>learn more<\/span><\/a>            <\/div>\n                  <\/div><!-- content -->\n\n                  <div class=\"cta__image launimation fadeIn\">\n            <img decoding=\"async\" loading=\"lazy\" sizes=\"auto, \" src=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/06\/Mashreghi_group-150x84.jpg\" data-src=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/06\/Mashreghi_group-1024x576.jpg\" data-srcset=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/06\/Mashreghi_group-e1753349641355.jpg 1920w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/06\/Mashreghi_group-e1753349641355.jpg 1600w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/06\/Mashreghi_group-1366x768.jpg 1366w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/06\/Mashreghi_group-1024x576.jpg 1024w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/06\/Mashreghi_group-768x432.jpg 768w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/06\/Mashreghi_group-550x309.jpg 550w\" class=\"\" alt=\"\"  width=\"1024\"  height=\"576\">          <\/div>\n              <\/div><!-- wrapper -->\n\n    <\/div><!-- container -->\n  <\/section>\n\n\n\n\n  <section id=\"ebv-reactivation-as-a-key-mechanism-of-mis-c-after-sars-cov-2-infection\"    class=\"section featured-post alignwide bg bg--full-width bg--aqua-100\">\n    <div class=\"container container--center\">\n      <div class=\"featured-post__container\">\n        <div class=\"featured-post__content launimation slideBottom\">\n                      <div class=\"featured-post__info\">\n                              \n<ul class=\"tag-pills\" >\n      <li >\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        For patients      <\/span>\n    <\/li>\n      <li >\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        Publications      <\/span>\n    <\/li>\n  <\/ul>                                                          <time class=\"featured-post__date date\" datetime=\"2025-03-07 15:00:12\">07.03.2025<\/time>                          <\/div>\n                                <h2 class=\"featured-post__title h2\" lang=\"en          \">EBV reactivation as a key mechanism of MIS-C after SARS-CoV-2 infection<\/h2>\n          \n                      <p class=\"featured-post__text\">Why children become seriously ill weeks after a Covid-19 infection and how they can be cured Researchers from Dr. Mir-Farzin Mashreghi\u2019s group from the German\u2026<\/p>\n          \n          <a class=\"featured-post__button button button--arrow button--arrow-link\"\n            href=\"https:\/\/www.drfz.de\/en\/neuigkeiten\/ebv-reactivation-as-a-key-mechanism-of-mis-c-after-sars-cov-2-infection\/\"><span\n              class=\"visually-hidden\">EBV reactivation as a key mechanism of MIS-C after SARS-CoV-2 infection<\/span><\/a>\n      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<\/div>\n\n    <div class=\"teaser-post__body\">\n      <time class=\"date\" datetime=\"2025-11-10 16:00:20\">10.11.2025<\/time>\n      <div class=\"teaser-post__title h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/neuigkeiten\/on-the-trail-of-a-mysterious-childhood-disease-the-story-of-ace-and-research-into-pims\/\" aria-describedby=\"post-20167\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          On the trail of a mysterious childhood disease\u2014The story of Ace and research into PIMS        <\/a>\n      <\/div>\n\n              <div class=\"teaser-post__excerpt ellipsis\">\n          Tilmann Kallinich and Mir-Farzin Mashreghi in Leibniz Magazine In Leibniz Magazine, Fabian Zapatka tells the story of six-year-old Ace Jaite, representing many children with Pediatric\u2026        <\/div>\n          <\/div>\n  <\/div>\n<\/article>              <\/div>\n                          <div class=\"swiper-slide\">\n                \n<article\n  id=\"post-19854\" 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rel=\"bookmark\">\n          Carl Goetzke is awarded the Albert Czerny Prize        <\/a>\n      <\/div>\n\n              <div class=\"teaser-post__excerpt ellipsis\">\n          Recognition for outstanding achievements in pediatric and adolescent medicine This year, the German Society for Pediatrics and Adolescent Medicine (DGKJ) awarded the prestigious Adalbert Czerny\u2026        <\/div>\n          <\/div>\n  <\/div>\n<\/article>              <\/div>\n                          <div class=\"swiper-slide\">\n                \n<article\n  id=\"post-19726\" class=\"teaser-post box box--min-height launimation slideBottom graded-box post-19726 post type-post status-publish format-standard has-post-thumbnail hentry category-for-patients category-news-en tag-eicke-latz-en tag-kallinich tag-latz tag-mashreghi-en tag-program-area-1 tag-program-area-3 programme-area-tax-programme-area-1 programme-area-tax-programme-area-3 working-group-tax-chronic-inflammation-in-childhood working-group-tax-immunobiology-of-inflammation working-group-tax-therapeutic-gene-regulation\">\n  <div class=\"teaser-post__wrap\">\n    <div class=\"teaser-post__cats\">\n      \n<ul class=\"tag-pills tag-pills--small\" role=\"none\">\n      <li role=\"none\">\n      <span class=\"tag-pill\">\n        <span class=\"visually-hidden\">Kategorie: <\/span>\n        For patients      <\/span>\n    <\/li>\n  <\/ul>    <\/div>\n\n    <div class=\"teaser-post__body\">\n      <time class=\"date\" datetime=\"2025-09-29 08:55:20\">29.09.2025<\/time>\n      <div class=\"teaser-post__title h5\">\n        <a href=\"https:\/\/www.drfz.de\/en\/neuigkeiten\/three-drfz-researchers-as-the-top-100-minds-in-science-at-the-capital-in-2025\/\" aria-describedby=\"post-19726\"\n          title=\"Gehe zum Beitrag\" rel=\"bookmark\">\n          Three DRFZ researchers as the top 100 minds in science at the capital in 2025        <\/a>\n      <\/div>\n\n              <div class=\"teaser-post__excerpt ellipsis\">\n          Tilmann Kallinich, Eicke Latz, and Mir-Farzin Mashreghi were selected by the Tagesspiegel Prof. Dr. Tilmann Kallinich, Prof. Dr. Eicke Latz, and PD Dr. Mir-Farzin Mashreghi\u2026        <\/div>\n          <\/div>\n  <\/div>\n<\/article>              <\/div>\n            \n          <\/div><!-- swiper-wrapper -->\n\n                      <div class=\"slider__pagination slider__pagination--contained\">\n              <button class=\"slider__button-prev\"><\/button>\n              <button class=\"slider__button-next\"><\/button>\n            <\/div>\n          \n                      <div class=\"slider__skip-links-container\">\n              <a id=\"after-slider-block_a0fe55be9bb0e44239f1cce9a7f86bfd\"\n                 href=\"#before-slider-block_a0fe55be9bb0e44239f1cce9a7f86bfd\"\n                 class=\"skip-link\">Go to beginning of slider<\/a>\n            <\/div>\n                  <\/div>\n\n                          <div class=\"related-news__load-more 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","protected":false},"excerpt":{"rendered":"","protected":false},"author":9,"featured_media":1390,"menu_order":0,"template":"","department":[296],"function":[],"liaison":[],"programme-area-function":[520],"programme-area-tax":[181],"working-group-function":[521],"working-group-tax":[258],"class_list":["post-3991","head","type-head","status-publish","has-post-thumbnail","hentry","department-pa-3-systems-rheumatology","programme-area-function-leader","programme-area-tax-programme-area-3","working-group-function-group-leader","working-group-tax-therapeutic-gene-regulation"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dr. Mir-Farzin Mashreghi - DRFZ<\/title>\n<meta name=\"description\" content=\"Mir-Farzin Mashreghi heads the research group Therapeutic Gene Regulation at the German Rheumatology Research Center, a Leibniz Institute\" \/>\n<meta name=\"robots\" content=\"index, follow, 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