{"id":11230,"date":"2025-02-11T13:32:11","date_gmt":"2025-02-11T13:32:11","guid":{"rendered":"https:\/\/www.drfz.de\/tierversuche\/belastungen-zahlen-statistik\/"},"modified":"2026-01-05T12:34:57","modified_gmt":"2026-01-05T12:34:57","slug":"belastungen-zahlen-statistik","status":"publish","type":"page","link":"https:\/\/www.drfz.de\/en\/tierversuche\/belastungen-zahlen-statistik\/","title":{"rendered":"Severity degrees, numbers &amp; statistics"},"content":{"rendered":"\n  <section id=\"severity-degrees-numbers-statistics\"    class=\"section hero alignfull\">\n    <div class=\"hero__wrapper gradient gradient--hero\">\n      <div class=\"container container--center\">\n        <div class=\"hero__content launimation slideBottom\">\n                      <p class=\"hero__subheading\">An insight into the world of numbers<\/p>\n          \n                      <h1              class=\"hero__heading d1\">Severity degrees, numbers &amp; statistics<\/h1>\n          \n                  <\/div>\n      <\/div>\n\n              <img decoding=\"async\" loading=\"lazy\" sizes=\"auto, 100vw\" src=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/02\/MC_JHZ8441-150x100.jpg\" data-src=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/02\/MC_JHZ8441.jpg\" data-srcset=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/02\/MC_JHZ8441.jpg 1920w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/02\/MC_JHZ8441.jpg 1600w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/02\/MC_JHZ8441.jpg 1366w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/02\/MC_JHZ8441.jpg 1024w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/02\/MC_JHZ8441-768x511.jpg 768w, https:\/\/www.drfz.de\/wp-content\/uploads\/2025\/02\/MC_JHZ8441-550x366.jpg 550w\" class=\"hero__image\" alt=\"\"  width=\"800\"  height=\"532\">      \n      \n    <\/div><!-- content -->\n\n  <\/section>\n\n\n\n  <section id=\"severity-degrees-of-animal-experiments\"\n           class=\"section accordion  alignwide \"\n           data-open=\"multiple\">\n    <div class=\"container container--center container--medium\">\n              <h2 class=\"h3 section__heading launimation slideBottom\">Severity degrees of animal experiments<\/h2>\n      \n      \n      \n              <div id=\"panel-\"\n             class=\"accordion__category active\" role=\"tabpanel\"\n             aria-labelledby=\"tab-\">\n                    <script type=\"application\/ld+json\">\n            {\n              \"@context\": \"https:\/\/schema.org\",\n              \"@type\": \"FAQPage\",\n              \"mainEntity\": [{\"@type\": \"Question\",\"name\": \"Legal framework\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"The indispensability of each individual planned animal experiment must be examined and assessed against the expected stress for each individual animal. The following principle applies: the greater the expected burden on the animals, the greater the scientific benefit must be.\nThe expected burden on the animal is scientifically assessed and checked for ethical justifiability. The burden is not determined by the applicants. Instead, the researchers provide a personal severity assessment, which is critically reviewed by the animal welfare officers and then submitted to the approving authority. The authority then determines the final exposure of the animals for each experiment.\"}},{\"@type\": \"Question\",\"name\": \"European determination of load levels\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"When planning the experiment, care is taken to ensure that the severity imposed on the individual animal is kept as low as possible. The degree of severity for the overall experiment is determined according to the highest stress to be expected for the individual animal. This means that even if other groups of animals in an experiment are not exposed to stress (e.g. control animals), the entire experiment is still considered to be severely stressed if an individual animal can experience this stress.\"}},{\"@type\": \"Question\",\"name\": \"Definitions of the Severity Degrees\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"\u2018No recovery of vital function\u2019: This term is used for procedures that are performed entirely under general anaesthesia, from which the animal does not wake up, or when animals are killed for scientific purposes for subsequent organ removal (without prior treatment, intervention or manipulation). The latter accounts for by far the largest proportion of animals killed for experimental purposes and, although it is not considered an animal experiment according to the Animal Welfare Act, it is included in the annual laboratory animal report as the degree of stress \u2018no recovery of vital function\u2019.\n\u2018 Mild\u2019: Procedures that cause minor pain, suffering or harm to animals for a short period of time or do not cause significant impairment of the welfare or general condition of the animals are categorised as \u2018mild\u2019.\n\nExample: The subcutaneous injection of a drug.\n\n\u2018Moderate\u2019: Procedures that cause short-term moderate pain, suffering or harm to the animals or prolonged minor pain, as well as experiments that cause moderate impairment of the welfare or general condition of the animals, are classified as \u2018\u2019moderate\u2018\u2019.\n\nExample: The administration of anaesthesia with subsequent awakening.\n\n\u2018Severe\u201d: Procedures that cause severe pain, suffering or distress to the animals or prolonged moderate pain, suffering or harm, as well as procedures that cause severe impairment of the welfare or general condition of the animals, are classified as \u201csevere\u201d.\n\nExample: The induction of a clinical disease associated with partial paralysis.\"}}]\n            }\n          <\/script>\n\n          <div class=\"accordion__content\">\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69de8b893cfc1_0\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Legal framework<\/span>\n                                              <span class=\"accordion-item__title-subtitle\">An animal experiment is only permitted by law if the animal\u00b4s prospective pain, suffering or harm is ethically justifiable in regard of the purpose of the experiment.<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69de8b893cfc1_0\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>The indispensability of each individual planned animal experiment must be examined and assessed against the expected stress for each individual animal. The following principle applies: the greater the expected burden on the animals, the greater the scientific benefit must be.<\/p>\n<p>The expected burden on the animal is scientifically assessed and checked for ethical justifiability. The burden is not determined by the applicants. Instead, the researchers provide a personal severity assessment, which is critically reviewed by the animal welfare officers and then submitted to the approving authority. The authority then determines the final exposure of the animals for each experiment.<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69de8b893cfc1_1\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">European determination of load levels<\/span>\n                                              <span class=\"accordion-item__title-subtitle\">According to European legislation, a classification is made between the degrees of stress \u2018mild\u2019, \u201cmoderate\u201d, \u201csevere\u201d and \u2019no recovery of vital function\u2019.<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69de8b893cfc1_1\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>When planning the experiment, care is taken to ensure that the severity imposed on the individual animal is kept as low as possible. The degree of severity for the overall experiment is determined according to the highest stress to be expected for the individual animal. This means that even if other groups of animals in an experiment are not exposed to stress (e.g. control animals), the entire experiment is still considered to be severely stressed if an individual animal can experience this stress.<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"false\"\n                        aria-controls=\"accordion_69de8b893cfc1_2\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Definitions of the Severity Degrees<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69de8b893cfc1_2\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <ul>\n<li>\u2018No recovery of vital function\u2019: This term is used for procedures that are performed entirely under general anaesthesia, from which the animal does not wake up, or when animals are killed for scientific purposes for subsequent organ removal (without prior treatment, intervention or manipulation). The latter accounts for by far the largest proportion of animals killed for experimental purposes and, although it is not considered an animal experiment according to the Animal Welfare Act, it is included in the annual laboratory animal report as the degree of stress \u2018no recovery of vital function\u2019.<\/li>\n<li>\u2018 Mild\u2019: Procedures that cause minor pain, suffering or harm to animals for a short period of time or do not cause significant impairment of the welfare or general condition of the animals are categorised as \u2018mild\u2019.<\/li>\n<\/ul>\n<p>Example: The subcutaneous injection of a drug.<\/p>\n<ul>\n<li>\u2018Moderate\u2019: Procedures that cause short-term moderate pain, suffering or harm to the animals or prolonged minor pain, as well as experiments that cause moderate impairment of the welfare or general condition of the animals, are classified as \u2018\u2019moderate\u2018\u2019.<\/li>\n<\/ul>\n<p>Example: The administration of anaesthesia with subsequent awakening.<\/p>\n<ul>\n<li>\u2018Severe\u201d: Procedures that cause severe pain, suffering or distress to the animals or prolonged moderate pain, suffering or harm, as well as procedures that cause severe impairment of the welfare or general condition of the animals, are classified as \u201csevere\u201d.<\/li>\n<\/ul>\n<p>Example: The induction of a clinical disease associated with partial paralysis.<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                      <\/div>\n        <\/div>\n          <\/div>\n  <\/section>\n\n\n\n\n<section class=\"wp-block-group alignwide\">\n<section class=\"wp-block-group\">\n<h3 class=\"wp-block-heading toc-item\" id=\"numbers-drfz-statistics\">Numbers &amp; DRFZ Statistics<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.bf3r.de\/angebote\/versuchstierzahlen\/versuchstierzahlen-2024\/\"><u>In Germany, a total of 1.95 million vertebrate animals were used for scientific research in 2024.<\/u>\u00a0<\/a>This means that the number of laboratory animals in Germany has fallen compared to the previous year (2023: 2.413 million). The total number of animals includes 1.33 million animals used in animal experiments and 627,000 animals that were killed for scientific purposes without prior animal experimentation. Rodents, especially mice and rats, accounted for by far the largest proportion of all laboratory animals, at around 80 %.<br><\/li>\n\n\n\n<li><a href=\"https:\/\/www.bf3r.de\/assets\/01_Ver\u00f6ffentlichungen\/Versuchstierzahlen\/versuchstierzahlen-2024-aufgeschluesselt-nach-bundeslaendern-und-bundeswehr.xlsx\"><u>The use of a total of 127,095 laboratory animals in Berlin was reported for 2024,<\/u>\u00a0<\/a>which is around 5 % less than in the previous year (133,091 animals in 2023).<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Berlin has long been known as the \u2018capital of animal research\u2019. However, the high number of laboratory animals can be explained by the high density of research institutions.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>In 2024, 4251 animals were used for scientific research at the DRFZ. The number has increased slightly compared to the previous year (3,648 animals). The number of animals for 2022 was significantly lower at 2,215, which is due to reduced research activity during the coronavirus pandemic.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Did you know: For many experiments, it is necessary to determine the genotype of each animal born in order to ensure that only those animals in which the desired genetic modification for the respective scientific question has been inherited are selected for the experiment. In most cases, typing can be carried out from ear punch samples, which are collected during the individual marking of the animals in everyday animal care. However, some characteristics can only be determined by analysing blood samples. In the European Union, taking blood samples for this purpose is classified as animal experimentation. This means that the number of laboratory animals quickly increases when a new experimental project begins at an institute in which all bred animals have to be typed in advance by taking blood samples. This is another reason for fluctuations in the number of laboratory animals.<\/p>\n<\/section>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1031\" src=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-scaled.png\" alt=\"\" class=\"wp-image-20761\" srcset=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-scaled.png 2560w, https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-300x121.png 300w, https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-1024x412.png 1024w, https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-768x309.png 768w, https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-1536x619.png 1536w, https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-2048x825.png 2048w, https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-1920x773.png 1920w, https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-1600x644.png 1600w, https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-1366x550.png 1366w, https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-550x222.png 550w, https:\/\/www.drfz.de\/wp-content\/uploads\/2026\/01\/Grafik-EN-150x60.png 150w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/figure>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.tierversuche-verstehen.de\/versuchstierzahlen\/?gad_source=1&amp;gclid=EAIaIQobChMIwJGuweayhwMVqGZBAh3Nigu4EAAYASAAEgK0KPD_BwE\" target=\"_blank\" rel=\"noreferrer noopener\">Further information on the number of laboratory animals<\/a><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.drfz.de\/en\/tierversuche\/\" target=\"_blank\" rel=\"noreferrer noopener\">Home Animal experiments at DRFZ&nbsp;<\/a><\/div>\n<\/div>\n<\/section>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Numbers &amp; DRFZ Statistics Berlin has long been known as the \u2018capital of animal research\u2019. However, the high number of laboratory animals can be explained\u2026<\/p>\n","protected":false},"author":9,"featured_media":0,"parent":11168,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-11230","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Severity degrees, numbers &amp; statistics - DRFZ<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.drfz.de\/en\/tierversuche\/belastungen-zahlen-statistik\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Severity degrees, numbers &amp; statistics - DRFZ\" \/>\n<meta property=\"og:description\" content=\"Numbers &amp; DRFZ Statistics Berlin has long been known as the \u2018capital of animal research\u2019. 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