{"id":25141,"date":"2026-10-30T07:37:40","date_gmt":"2026-10-30T07:37:40","guid":{"rendered":"https:\/\/www.drfz.de\/?p=25141"},"modified":"2026-10-30T07:37:40","modified_gmt":"2026-10-30T07:37:40","slug":"molecular-causes-of-rheumatic-diseases-and-new-treatment-options","status":"publish","type":"post","link":"https:\/\/www.drfz.de\/en\/neuigkeiten\/molecular-causes-of-rheumatic-diseases-and-new-treatment-options\/","title":{"rendered":"Molecular Causes of Rheumatic Diseases and New Treatment Options"},"content":{"rendered":"\n

A review in<\/em> Nature on disease mechanisms, targeted therapies, and potential prospects for a cure<\/em><\/h3>\n\n\n\n

Inflammatory rheumatic diseases such as rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus result from a dysregulation of the innate and adaptive immune systems.<\/p>\n\n\n\n

Prof. Dr. Eicke Latz from German Rheumatology Research Center Berlin, a Leibniz Institute, and Prof. Dr. Gerhard Kr\u00f6nke from the Department of Medicine with a focus on Rheumatology and Clinical Immunology at Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, in collaboration with Prof. Dr. Georg Schett of Department of Medicine 3 \u2014 Rheumatology and Immunology, University Hospital Erlangen, provide an overview of current findings on the molecular basis of these diseases. In the review, published in the renowned journal Nature<\/em>, the authors demonstrate how new targets and innovative therapeutic strategies are improving the treatment of chronic inflammatory rheumatic diseases. These developments also open up new perspectives with the goal of a cure.<\/p>\n\n\n\n

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Original publication<\/h2>\n \n \n
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\n \n Kr\u00f6nke G, Schett G, Latz E. Molecular underpinnings of rheumatic diseases and emerging therapeutic concepts. Nature. 2026 Oct;658(8138):1141-1152. doi: 10.1038\/s41586-026-10966-x. Epub 2026 Oct 28. PMID: 42951953.<\/a>\n\n \n \n <\/span>\n <\/a>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/section>\n\n\n\n\n
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Authors from DRFZ<\/h2>\n \n <\/div>\n \n
\n \n\n
\n \"Portraitfoto <\/div>\n
\n

Prof. Dr. med. Eicke Latz<\/h2>\n
\n

Wissenschaftlicher Direktor<\/p>\n

\n Gruppenleitung: Immunbiologie der Entz\u00fcndung <\/p>\n <\/div>\n <\/div>\n\n

\n

eicke.latz@drfz.de<\/a><\/p>\n <\/div>\n Prof. Dr. med. Eicke Latz<\/span><\/a>\n<\/article>\n\n

\n \"\" <\/div>\n
\n

Prof. Dr. Gerhard Kr\u00f6nke<\/h2>\n
\n Liaison working group with Charit\u00e9 – Rheumatologie und Klinische Immunologie<\/p>\n <\/div>\n <\/div>\n\n
\n

gerhard.kroenke@charite.de<\/a><\/p>\n <\/div>\n Prof. Dr. Gerhard Kr\u00f6nke<\/span><\/a>\n<\/article> <\/div>\n <\/div>\n <\/section>\n","protected":false},"excerpt":{"rendered":"

A review in Nature on disease mechanisms, targeted therapies, and potential prospects for a cure Inflammatory rheumatic diseases such as rheumatoid arthritis, psoriatic arthritis, and\u2026<\/p>\n","protected":false},"author":4,"featured_media":25157,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[292,291],"tags":[635,448,492,497],"programme-area-tax":[179,182],"working-group-tax":[253,250],"class_list":["post-25141","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-en","category-publications","tag-eicke-latz-en","tag-latz","tag-program-area-1","tag-program-area-4","programme-area-tax-programme-area-1","programme-area-tax-programme-area-4","working-group-tax-clinical-rheumatology","working-group-tax-immunobiology-of-inflammation"],"acf":[],"yoast_head":"\nMolecular Causes of Rheumatic Diseases and New Treatment Options - 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