{"id":8294,"date":"2024-12-20T17:58:00","date_gmt":"2024-12-20T17:58:00","guid":{"rendered":"https:\/\/www.drfz.de\/news\/das-auge-als-fenster-zum-gehirn\/"},"modified":"2025-02-07T07:34:58","modified_gmt":"2025-02-07T07:34:58","slug":"das-auge-als-fenster-zum-gehirn","status":"publish","type":"post","link":"https:\/\/www.drfz.de\/en\/neuigkeiten\/das-auge-als-fenster-zum-gehirn\/","title":{"rendered":"The eye as a window to the brain"},"content":{"rendered":"\n

Anja Hauser and Raluca Niesner from the DRFZ, together with colleagues from Charit\u00e9  \u2013  Universit\u00e4tsmedizin Berlin, have published a new study on retinal imaging in the journal Neurology, Neuroimmunology and Neuroinflammation<\/em>.<\/p>\n\n\n\n

The researchers developed a special microscope that combines optical coherence tomography (OCT) and two-photon microscopy. This enabled them to record non-invasive time-lapse videos of the retina in a multiple sclerosis model over several weeks. While OCT is already used in clinical diagnostics, two-photon microscopy allows additional functional, dynamic analysis.<\/p>\n\n\n\n

Using this new technique, they discovered that certain (CX3CR1+) immune cells migrate to the optic nerve head at an early stage \u2013 an indication of the disease even before symptoms appear. This research demonstrates the importance of combined structural and functional imaging for early detection in neuroinflammatory and neurodegenerative diseases. This in turn enables timely intervention in the course of the disease.<\/p>\n\n\n\n

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\n \"\" <\/div>\n
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Prof. Dr. med. vet. Anja Erika Hauser<\/h2>\n
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\n Leader: Programme Area 1, PA 1 \u2013 Cell and Tissue Rheumatology <\/p>\n

\n Group leader: Immune Dynamics <\/p>\n Liaison working group with Charit\u00e9 – Rheumatology and Clinical Immunology<\/p>\n <\/div>\n <\/div>\n\n

\n

hauser@drfz.de<\/a><\/p>\n <\/div>\n Prof. Dr. med. vet. Anja Erika Hauser<\/span><\/a>\n<\/article>\n\n

\n \"\" <\/div>\n
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Prof. Dr. rer. nat. Raluca Niesner<\/h2>\n
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\n Programme Area 1, PA 1 \u2013 Cell and Tissue Rheumatology <\/p>\n

\n Group leader: Biophysical Analytics <\/p>\n Liaison working group with FU Berlin<\/p>\n <\/div>\n <\/div>\n\n

\n

niesner@drfz.de<\/a><\/p>\n <\/div>\n Prof. Dr. rer. nat. Raluca Niesner<\/span><\/a>\n<\/article> <\/div>\n <\/div>\n <\/section>\n\n\n\n

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\n \n original publication<\/a>\n\n Raspe R, G\u00fcnther R, Uecker R, Rakhymzhan A, Paul F, Radbruch H, Niesner RA, Hauser AE. Multimodal Longitudinal Optical Imaging Reveals Optic Neuritis Preceding Retinal Pathology in Experimental Autoimmune Encephalomyelitis. Neurol Neuroimmunol Neuroinflamm. 2025 Jan;12(1):e200338. doi: 10.1212\/NXI.0000000000200338. Epub 2024 Dec 4. PMID: 39661921; PMCID: PMC11637508.<\/span>\n \n \n <\/span>\n <\/a>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/section>\n\n","protected":false},"excerpt":{"rendered":"

Anja Hauser and Raluca Niesner from the DRFZ, together with colleagues from Charit\u00e9  \u2013  Universit\u00e4tsmedizin Berlin, have published a new study on retinal imaging in\u2026<\/p>\n","protected":false},"author":4,"featured_media":4689,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[291],"tags":[447,401,492],"programme-area-tax":[179],"working-group-tax":[242,251],"class_list":["post-8294","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publications","tag-hauser-en","tag-immunodynamics","tag-program-area-1","programme-area-tax-programme-area-1","working-group-tax-biophysical-analytics","working-group-tax-immune-dynamics"],"acf":[],"yoast_head":"\nThe eye as a window to the brain - DRFZ<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.drfz.de\/en\/neuigkeiten\/das-auge-als-fenster-zum-gehirn\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The eye as a window to the brain - 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