{"id":16220,"date":"2023-01-23T11:00:00","date_gmt":"2023-01-23T11:00:00","guid":{"rendered":"https:\/\/www.drfz.de\/?post_type=project&#038;p=16220"},"modified":"2025-04-01T11:35:08","modified_gmt":"2025-04-01T11:35:08","slug":"icon","status":"publish","type":"project","link":"https:\/\/www.drfz.de\/en\/forschungsprojekte\/icon\/","title":{"rendered":"ICON"},"content":{"rendered":"\n<h2 class=\"wp-block-heading alignwide toc-item\" id=\"current-projects\"><strong><strong>Current projects<\/strong><\/strong><\/h2>\n\n\n\n<section class=\"wp-block-group alignwide\">\n<p class=\"alignwide has-text-align-wide wp-block-paragraph\"><strong>Data from the ICON early cohort are currently being used to<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>estimate the health care costs of JIA (PAVE)<\/li>\n\n\n\n<li>examine the familial burden of the disease (PAVE)<\/li>\n\n\n\n<li>analyze the utilization of and satisfaction with health care services over time (DZKJ)<\/li>\n\n\n\n<li>to determine the progression of health and risk behavior in adolescents with juvenile idiopathic arthritis compared to controls (DZKJ)<\/li>\n\n\n\n<li>to compare the life satisfaction of adolescents with JIA with that of age-appropriate controls&nbsp;<\/li>\n\n\n\n<li>to record the emotional strain and health-related quality of life of children and adolescents with juvenile idiopathic arthritis over the course of the disease and to determine associated factors<\/li>\n\n\n\n<li>to examine differences between the perception of disease activity in JIA by children, parents and doctors and to identify factors that explain these differences (DZKJ)<\/li>\n\n\n\n<li>to determine drop-out rates over time and to understand the reasons for them (DZKJ)<\/li>\n<\/ul>\n<\/section>\n\n\n\n  <section id=\"selected-publications\"\n           class=\"section related-publications alignwide related-publications--slider \">\n    <div class=\"container container--center\">\n\n              <div class=\"section__heading-container launimation slideBottom\">\n                      <h2 class=\"section__heading\">Selected Publications<\/h2>\n                            <\/div>\n      \n              <div class=\"section__description wysiwyg launimation slideBottom\">\n          1. What is the short- and long-term prognosis for a child with JIA today?        <\/div>\n      \n      <div class=\"related-publications__slider swiper swiper-pull-right\">\n                  <div class=\"slider__skip-links-container\">\n            <a id=\"before-slider-block_94d8df6bd653b4bb83e14b594a70b2ac\"\n               href=\"#after-slider-block_94d8df6bd653b4bb83e14b594a70b2ac\"\n               class=\"slider-skip-link\">Gehe zum Ende des Sliders<\/a>\n          <\/div>\n        \n        <div class=\"swiper-wrapper grid\">\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-8076\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-8076 publication type-publication status-publish hentry year-tax-399\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Milatz F, Pedersen MJ, Klotsche , Liedmann I, Martina Niewerth M, Hospach A, Horneff G, Klein A, Weller-Heinemann F, Foeldvari I, Kallinich T, Haas JP, Windschall D, Dressler F, Foell D, Kuemmerle-Deschner JB, Minden K, Minden K.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/39434096\" target=\"_blank\" lang=\"en\">Physical (in)activity and screen-based media use of adolescents with juvenile idiopathic arthritis over time &#8211; data from a German inception cohort.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\">Pediatr Rheumatol Online J. 2024 Oct 21;22(1):93. doi: 10.1186\/s12969-024-01027-6. PMID: 39434096; PMCID: PMC11492743.<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/39434096\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-8076\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Physical (in)activity and screen-based media use of adolescents with juvenile idiopathic arthritis over time - data from a German inception cohort.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-6457\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-6457 publication type-publication status-publish hentry year-tax-368\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Sengler C.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/link.springer.com\/article\/10.1007%2Fs00393-019-0648-1\" target=\"_blank\" lang=\"en\">Neue Therapiewege, bessere Outcomes? : Ergebnisse aus Inzeptionskohorten fur Patienten mit juveniler idiopathischer Arthritis. [New therapy approaches, better outcomes? : Results from inception cohorts for patients with juvenile idiopathic arthritis].<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\">Z Rheumatol. 2019<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/link.springer.com\/article\/10.1007%2Fs00393-019-0648-1\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-6457\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Neue Therapiewege, bessere Outcomes? : Ergebnisse aus Inzeptionskohorten fur Patienten mit juveniler idiopathischer Arthritis. [New therapy approaches, better outcomes? : Results from inception cohorts for patients with juvenile idiopathic arthritis].<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-5891\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-5891 publication type-publication status-publish hentry year-tax-393\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Sengler C, Klotsche J, Niewerth M, Liedmann I, F\u00f6ll D, Heiligenhaus A, Ganser G, Horneff G, Haas JP, Minden K.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/rmdopen.bmj.com\/content\/1\/1\/e000074\" target=\"_blank\" lang=\"en\">The majority of newly diagnosed patients with juvenile idiopathic arthritis reach an inactive disease state within the first year of specialised care: data from a German inception cohort.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\">RMD Open. 2015 Dec 8;1(1):e000074. <\/div>\n      <\/div>\n      <!--a href=\"http:\/\/rmdopen.bmj.com\/content\/1\/1\/e000074\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-5891\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">The majority of newly diagnosed patients with juvenile idiopathic arthritis reach an inactive disease state within the first year of specialised care: data from a German inception cohort.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-5454\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-5454 publication type-publication status-publish hentry year-tax-80\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Listing M, M\u00f6nkem\u00f6ller K, Liedmann I, Niewerth M, Sengler C, Listing J, Foell D, Heiligenhaus A, Klein A, Aklein A, Horneff G, Ganser G, Haas JP, Klotsche J, Minden K.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/arthritis-research.biomedcentral.com\/articles\/10.1186\/s13075-018-1588-x\" target=\"_blank\" lang=\"en\">The majority of patients with newly diagnosed juvenile idiopathic arthritis achieve a health-related quality of life that is similar to that of healthy peers: results of the German multicenter inception cohort (ICON).<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\">Arthritis Res Ther. 2018;20(1):106.<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/arthritis-research.biomedcentral.com\/articles\/10.1186\/s13075-018-1588-x\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-5454\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">The majority of patients with newly diagnosed juvenile idiopathic arthritis achieve a health-related quality of life that is similar to that of healthy peers: results of the German multicenter inception cohort (ICON).<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n          \n        <\/div><!-- swiper-wrapper -->\n\n                  <div class=\"slider__pagination slider__pagination--contained\">\n            <button class=\"slider__button-prev\"><\/button>\n            <button class=\"slider__button-next\"><\/button>\n          <\/div>\n        \n                  <div class=\"slider__skip-links-container\">\n            <a id=\"after-slider-block_94d8df6bd653b4bb83e14b594a70b2ac\"\n               href=\"#before-slider-block_94d8df6bd653b4bb83e14b594a70b2ac\"\n               class=\"skip-link\">Gehe zum Anfang des Sliders<\/a>\n          <\/div>\n              <\/div>\n\n\n                <\/div><!-- container -->\n  <\/section>\n\n\n\n\n  <section id=\"block_972fc1c833a3159b2e2731ab9d0ce85a\"\n           class=\"section related-publications alignwide related-publications--slider \">\n    <div class=\"container container--center\">\n\n      \n              <div class=\"section__description wysiwyg launimation slideBottom\">\n          2. Is the JIA outcome predictable?\r\n        <\/div>\n      \n      <div class=\"related-publications__slider swiper swiper-pull-right\">\n                  <div class=\"slider__skip-links-container\">\n            <a id=\"before-slider-block_972fc1c833a3159b2e2731ab9d0ce85a\"\n               href=\"#after-slider-block_972fc1c833a3159b2e2731ab9d0ce85a\"\n               class=\"slider-skip-link\">Gehe zum Ende des Sliders<\/a>\n          <\/div>\n        \n        <div class=\"swiper-wrapper grid\">\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-7529\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-7529 publication type-publication status-publish hentry year-tax-396\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Straalen JV, Kearsley-Fleet L, Klotsche , De Roock S, Minden K, Heiligenhaus A, Hyrich KL, Boer JD, Lamot L, Olivieri AN, Gallizzi R, Smolewska E, Faugier E, Pastore S, Hashkes PJ, Herrera CN, Emminger W, Consolini R, Wulffraat NM, Ruperto N, Swart JF.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/36054539\" target=\"_blank\" lang=\"en\">Development and external validation of a model predicting new-onset chronic uveitis at different disease durations in juvenile idiopathic arthritis.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\">Arthritis Rheumatol. 2023 Feb;75(2):318-327. doi: 10.1002\/art.42329. Epub 2022 Dec 13. PMID: 36054539.<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/36054539\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-7529\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Development and external validation of a model predicting new-onset chronic uveitis at different disease durations in juvenile idiopathic arthritis.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-5394\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-5394 publication type-publication status-publish hentry year-tax-80\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Haasnoot AJW, Schilham MW, Kamphuis S, Hissink Muller PCE, Heiligenhaus A, Foell D, Minden K, Ophoff RA, Radstake TRDJ, Den Hollander AI, Reinards THCM, Hiddingh S, Schalij-Delfos NE, Hoppenreijs EPAH, van Rossum MAJ, Wouters C, Saurenmann RK, van den Berg JM, Wulffraat N, Ten Cate R, de Boer JH, Pulit SL, Kuiper JJW.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/art.40484\" target=\"_blank\" lang=\"en\">Identification of an Amino Acid Motif in HLA-DRbeta1 That Distinguishes Uveitis in Patients With Juvenile Idiopathic Arthritis.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\">Arthritis Rheumatol. 2018;70(7):1155-1165.<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/art.40484\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-5394\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Identification of an Amino Acid Motif in HLA-DRbeta1 That Distinguishes Uveitis in Patients With Juvenile Idiopathic Arthritis.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n          \n        <\/div><!-- swiper-wrapper -->\n\n                  <div class=\"slider__pagination slider__pagination--contained\">\n            <button class=\"slider__button-prev\"><\/button>\n            <button class=\"slider__button-next\"><\/button>\n          <\/div>\n        \n                  <div class=\"slider__skip-links-container\">\n            <a id=\"after-slider-block_972fc1c833a3159b2e2731ab9d0ce85a\"\n               href=\"#before-slider-block_972fc1c833a3159b2e2731ab9d0ce85a\"\n               class=\"skip-link\">Gehe zum Anfang des Sliders<\/a>\n          <\/div>\n              <\/div>\n\n\n                <\/div><!-- container -->\n  <\/section>\n\n\n\n\n  <section id=\"block_385cd2282c212ac02f2ea4c58a39210b\"\n           class=\"section related-publications alignwide related-publications--slider \">\n    <div class=\"container container--center\">\n\n      \n              <div class=\"section__description wysiwyg launimation slideBottom\">\n          3. What influence does the occurrence of uveitis have on the outcome and in particular on the quality of life of the affected children and adolescents?\r\n        <\/div>\n      \n      <div class=\"related-publications__slider swiper swiper-pull-right\">\n                  <div class=\"slider__skip-links-container\">\n            <a id=\"before-slider-block_385cd2282c212ac02f2ea4c58a39210b\"\n               href=\"#after-slider-block_385cd2282c212ac02f2ea4c58a39210b\"\n               class=\"slider-skip-link\">Gehe zum Ende des Sliders<\/a>\n          <\/div>\n        \n        <div class=\"swiper-wrapper grid\">\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-6865\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-6865 publication type-publication status-publish hentry year-tax-394\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Walscheid K, Klotsche , Tappeiner C, Niewerth-Liepold , Foell D, Minden , Heiligenhaus A.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32105591\" target=\"_blank\" lang=\"en\">Adherence to ophthalmological screening recommendations and course of uveitis in children with juvenile idiopathic arthritis: data from the Inception Cohort of Newly diagnosed patients with JIA (ICON-JIA) study.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\"> Clin Exp Rheumatol. 2020 Jul-Aug;38(4):792-798. Epub 2020 Feb 19.<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32105591\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-6865\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Adherence to ophthalmological screening recommendations and course of uveitis in children with juvenile idiopathic arthritis: data from the Inception Cohort of Newly diagnosed patients with JIA (ICON-JIA) study.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-6203\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-6203 publication type-publication status-publish hentry year-tax-368\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Heiligenhaus A, Klotsche J, Tappeiner C, Sengler C, Niewerth M, Liedmann I, Hoeft S, Walscheid K, Lavric M, Foell D, Minden K.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/academic.oup.com\/rheumatology\/advance-article\/doi\/10.1093\/rheumatology\/key406\/5262280\" target=\"_blank\" lang=\"en\">Predictive factors and biomarkers for the 2-year outcome of uveitis in juvenile idiopathic arthritis: data from the Inception Cohort of Newly diagnosed patients with Juvenile Idiopathic Arthritis (ICON-JIA) study.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\">Rheumatology (Oxford).<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/academic.oup.com\/rheumatology\/advance-article\/doi\/10.1093\/rheumatology\/key406\/5262280\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-6203\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Predictive factors and biomarkers for the 2-year outcome of uveitis in juvenile idiopathic arthritis: data from the Inception Cohort of Newly diagnosed patients with Juvenile Idiopathic Arthritis (ICON-JIA) study.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-5546\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-5546 publication type-publication status-publish hentry year-tax-80\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Tappeiner C, Klotsche J, Sengler C, Niewerth M, Liedmann I, Walscheid K, Lavric M, Foell D, Minden K, Heiligenhaus A.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/art.40544\" target=\"_blank\" lang=\"en\">Risk Factors and Biomarkers for the Occurrence of Uveitis in Juvenile Idiopathic Arthritis: Data From the Inception Cohort of Newly Diagnosed Patients With Juvenile Idiopathic Arthritis Study.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\">Arthritis Rheumatol. 2018<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/art.40544\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-5546\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Risk Factors and Biomarkers for the Occurrence of Uveitis in Juvenile Idiopathic Arthritis: Data From the Inception Cohort of Newly Diagnosed Patients With Juvenile Idiopathic Arthritis Study.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n          \n        <\/div><!-- swiper-wrapper -->\n\n                  <div class=\"slider__pagination slider__pagination--contained\">\n            <button class=\"slider__button-prev\"><\/button>\n            <button class=\"slider__button-next\"><\/button>\n          <\/div>\n        \n                  <div class=\"slider__skip-links-container\">\n            <a id=\"after-slider-block_385cd2282c212ac02f2ea4c58a39210b\"\n               href=\"#before-slider-block_385cd2282c212ac02f2ea4c58a39210b\"\n               class=\"skip-link\">Gehe zum Anfang des Sliders<\/a>\n          <\/div>\n              <\/div>\n\n\n                <\/div><!-- container -->\n  <\/section>\n\n\n\n\n  <section id=\"block_2edd58632e82356979dbc93598e9be58\"\n           class=\"section related-publications alignwide related-publications--slider \">\n    <div class=\"container container--center\">\n\n      \n              <div class=\"section__description wysiwyg launimation slideBottom\">\n          4. Are biomarkers such as S100 proteins and cytokine profiles suitable for predicting the course of the disease?\r\n        <\/div>\n      \n      <div class=\"related-publications__slider swiper swiper-pull-right\">\n                  <div class=\"slider__skip-links-container\">\n            <a id=\"before-slider-block_2edd58632e82356979dbc93598e9be58\"\n               href=\"#after-slider-block_2edd58632e82356979dbc93598e9be58\"\n               class=\"slider-skip-link\">Gehe zum Ende des Sliders<\/a>\n          <\/div>\n        \n        <div class=\"swiper-wrapper grid\">\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-7314\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-7314 publication type-publication status-publish hentry year-tax-397\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Schulz C, Fuehner S, Schl\u00fcter B, Fobker M, Sengler C, Klotsche , Martina Niewerth M, Minden K, Foell D.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35109858\" target=\"_blank\" lang=\"en\">Prevalence of autoantibodies in patients with juvenile idiopathic arthritis: results from the German inception cohort ICON-JIA.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\"> Pediatr Rheumatol Online J. 2022 Feb 2;20(1):8. doi: 10.1186\/s12969-022-00668-9.<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35109858\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-7314\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Prevalence of autoantibodies in patients with juvenile idiopathic arthritis: results from the German inception cohort ICON-JIA.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-7043\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-7043 publication type-publication status-publish hentry year-tax-395\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Ganeva M, Fuehner S, Kessel C, Klotsche , Martina Niewerth M, Minden K, Foell D, Hinze CH, Wittkowski H.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33933108\" target=\"_blank\" lang=\"en\">Trajectories of disease courses in the inception cohort of newly diagnosed patients with JIA (ICON-JIA): the potential of serum biomarkers at baseline.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\"> Pediatr Rheumatol Online J. 2021 May 1;19(1):64. doi: 10.1186\/s12969-021-00553-x.<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33933108\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-7043\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Trajectories of disease courses in the inception cohort of newly diagnosed patients with JIA (ICON-JIA): the potential of serum biomarkers at baseline.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-6189\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-6189 publication type-publication status-publish hentry year-tax-80\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Sengler C, Zink J, Klotsche J, Niewerth M, Liedmann I, Horneff G, Kessel C, Ganser G, Thon A, Haas JP, Hospach A, Weller-Heinemann F, Heiligenhaus A, Foell D, Zink A, Minden K.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/arthritis-research.biomedcentral.com\/articles\/10.1186\/s13075-018-1765-y\" target=\"_blank\" lang=\"en\">Vitamin D deficiency is associated with higher disease activity and the risk for uveitis in juvenile idiopathic arthritis &#8211; data from a German inception cohort.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\">Arthritis Res Ther. 2018 Dec 13;20(1):276. <\/div>\n      <\/div>\n      <!--a href=\"http:\/\/arthritis-research.biomedcentral.com\/articles\/10.1186\/s13075-018-1765-y\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-6189\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Vitamin D deficiency is associated with higher disease activity and the risk for uveitis in juvenile idiopathic arthritis - data from a German inception cohort.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-4998\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-4998 publication type-publication status-publish hentry year-tax-391\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Ombrello MJ, Arthur VL, Remmers EF, Hinks A, Tachmazidou I, Grom AA, Foell D, Martini A, Gattorno M, \u00d6zen S, Prahalad S, Zeft AS, Bohnsack JF, Ilowite NT, Mellins ED, Russo R, Len C, Hilario MOE, Oliveira S, Yeung RSM, Rosenberg AM, Wedderburn LR, Anton J, Haas JP, Rosen-Wolff A, Minden K, Tenbrock K, Demirkaya E, Cobb J, Baskin E, Signa S, Shuldiner E, Duerr RH, Achkar JP, Kamboh MI, Kaufman KM, Kottyan LC, Pinto D, Scherer SW, Alarcon-Riquelme ME, Docampo E, Estivill X, Gul A, Langefeld CD, Thompson S, Zeggini E, Kastner DL, Woo P, Thomson W.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/ard.bmj.com\/content\/76\/5\/906.long\" target=\"_blank\" lang=\"en\">Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\"> Ann Rheum Dis. 2017;76(5):906-913.<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/ard.bmj.com\/content\/76\/5\/906.long\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-4998\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n          \n        <\/div><!-- swiper-wrapper -->\n\n                  <div class=\"slider__pagination slider__pagination--contained\">\n            <button class=\"slider__button-prev\"><\/button>\n            <button class=\"slider__button-next\"><\/button>\n          <\/div>\n        \n                  <div class=\"slider__skip-links-container\">\n            <a id=\"after-slider-block_2edd58632e82356979dbc93598e9be58\"\n               href=\"#before-slider-block_2edd58632e82356979dbc93598e9be58\"\n               class=\"skip-link\">Gehe zum Anfang des Sliders<\/a>\n          <\/div>\n              <\/div>\n\n\n                <\/div><!-- container -->\n  <\/section>\n\n\n\n\n  <section id=\"block_fe4f6be40314a97d49cc4ecf1c4ce0e9\"\n           class=\"section related-publications alignwide related-publications--slider \">\n    <div class=\"container container--center\">\n\n      \n              <div class=\"section__description wysiwyg launimation slideBottom\">\n          5. What economic burden does JIA place on those affected and on society?\r\n\r\n6. Are there deficits in care with prognostic relevance?        <\/div>\n      \n      <div class=\"related-publications__slider swiper swiper-pull-right\">\n        \n        <div class=\"swiper-wrapper grid\">\n                      <div class=\"swiper-slide\">\n              \n<article id=\"post-7005\"\n  class=\"teaser-publication box launimation slideBottom layout-box post-7005 publication type-publication status-publish hentry year-tax-395\">\n  <div class=\"teaser-publication__wrap\">\n          <div class=\"teaser-publication__authors ellipsis ellipsis--1\">Heinrich-Rohr M, M\u00f6nkem\u00f6ller K, Martina Niewerth M, Sengler C, Liedmann I, Kallinich T, Horneff G, Windschall D, Haas JP, Dressler F, Foeldvari I, Weller-Heinemann F, Hospach T, Kuemmerle-Deschner J, F\u00f6ll D, Klotsche , Minden K.<\/div>\n    \n    <div class=\"teaser-publication__title h6 ellipsis\">\n      <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33822700\" target=\"_blank\" lang=\"en\">Consumer perspective on healthcare services for juvenile idiopathic arthritis: results of a multicentre JIA inception cohort study.<\/a>\n    <\/div>\n\n          <div class=\"teaser-publication__source\"> Clin Exp Rheumatol. 2021 Mar 30.<\/div>\n      <\/div>\n      <!--a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33822700\" target=\"_blank\" class=\"teaser-publication__link\"\n      aria-describedby=\"post-7005\" tabindex=\"-1\" rel=\"bookmark\">\n      <span class=\"button button--arrow button--arrow-nw button--arrow-link\"><span\n          class=\"visually-hidden\">Consumer perspective on healthcare services for juvenile idiopathic arthritis: results of a multicentre JIA inception cohort study.<\/span><\/span>\n    <\/a-->\n  <\/article>\n            <\/div>\n          \n        <\/div><!-- swiper-wrapper -->\n\n        \n              <\/div>\n\n\n                <\/div><!-- container -->\n  <\/section>\n\n\n\n\n  <section id=\"team\"\n           class=\"section accordion  alignwide \"\n           data-open=\"single\">\n    <div class=\"container container--center container--medium\">\n              <h2 class=\"h3 section__heading launimation slideBottom\">Team<\/h2>\n      \n      \n              <div class=\"accordion__filters\">\n          \n<div class=\"pills swiper\" data-has-aria=\"1\" data-event=\"accordionCategoryChanged\">\n  <div class=\"pills__wrap swiper-wrapper\" role=\"tablist\">\n    <button id=\"tab-members\" class=\"pill swiper-slide\" aria-selected=\"true\" aria-controls=\"panel-members\">Members<\/button><button id=\"tab-collaborating-partners\" class=\"pill swiper-slide\" aria-selected=\"false\" aria-controls=\"panel-collaborating-partners\">Collaborating partners<\/button>  <\/div>\n<\/div>\n        <\/div>\n      \n              <div id=\"panel-members\"\n             class=\"accordion__category active\" role=\"tabpanel\"\n             aria-labelledby=\"tab-members\">\n                    <script type=\"application\/ld+json\">\n            {\n              \"@context\": \"https:\/\/schema.org\",\n              \"@type\": \"FAQPage\",\n              \"mainEntity\": [{\"@type\": \"Question\",\"name\": \"Members\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"Projekt coordination\nCindy Doerwald\nMartina Niewerth\nScientists\nJens Klotsche\nClaudia Sengler\nMiriam Listing\nDoctoral candidate\nSabine Kirchner, Ewelina T\u00fcrk, Meike Storms, Pascale Kurt, Julian Zink, Annalena Hauffe, Theresa Grunefeld\"}}]\n            }\n          <\/script>\n\n          <div class=\"accordion__content\">\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"true\"\n                        aria-controls=\"accordion_69f2589a5c4d3_0\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Members<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69f2589a5c4d3_0\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p><strong>Projekt coordination<\/strong><br \/>\nCindy Doerwald<br \/>\nMartina Niewerth<\/p>\n<p><strong>Scientists<\/strong><br \/>\nJens Klotsche<br \/>\nClaudia Sengler<br \/>\nMiriam Listing<\/p>\n<p><strong>Doctoral candidate<\/strong><br \/>\nSabine Kirchner, Ewelina T\u00fcrk, Meike Storms, Pascale Kurt, Julian Zink, Annalena Hauffe, Theresa Grunefeld<\/p>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                      <\/div>\n        <\/div>\n              <div id=\"panel-collaborating-partners\"\n             class=\"accordion__category \" role=\"tabpanel\"\n             aria-labelledby=\"tab-collaborating-partners\">\n                    <script type=\"application\/ld+json\">\n            {\n              \"@context\": \"https:\/\/schema.org\",\n              \"@type\": \"FAQPage\",\n              \"mainEntity\": [{\"@type\": \"Question\",\"name\": \"Collaborating partners\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"Das Projekt wurde gemeinsam mit der Augenabteilung am St. Franziskus Hospital in M\u00fcnster und der Klinik f\u00fcr P\u00e4diatrische Rheumatologie und Immunologie in M\u00fcnster durchgef\u00fchrt. Der Verbund kooperierte prim\u00e4r mit 11 kinderrheumatologischen Zentren. Im Verlauf kamen noch etwa 180 nicht prim\u00e4r involvierte p\u00e4diatrisch- und internistisch-rheumatologische Einrichtungen und etwa 400 augen\u00e4rztlichen Einrichtungen hinzu.\nAktuelle Vorhaben\n\u00a0\nDaten der ICON-Fr\u00fchkohorte werden derzeit genutzt, um\n\ndie Krankheitskosten der JIA zu sch\u00e4tzen (PAVE)\ndie famili\u00e4re Belastung durch die Erkrankung zu untersuchen (PAVE)\ndie Inanspruchnahme von und Zufriedenheit mit Versorgungsleistungen \u00fcber die Zeit zu analysieren (DZKJ)\nVerl\u00e4ufe von Gesundheits- und Risikoverhalten bei Jugendlichen mit juveniler idiopathischer Arthritis im Vergleich zu Kontrollen zu ermitteln (DZKJ)\ndie Lebenszufriedenheit Jugendlicher mit JIA mit jener altersentsprechender Kontrollen zu vergleichen\ndie emotionale Belastung und gesundheitsbezogene Lebensqualit\u00e4t von Kindern und Jugendlichen mit juveniler idiopathischer Arthritis im Krankheitsverlauf zu erfassen und assoziierte Faktoren zu ermitteln\nUnterschiede zwischen der Wahrnehmung der Krankheitsaktivit\u00e4t bei der JIA durch Kinder, Eltern und \u00c4rzte zu untersuchen und Faktoren zu identifizieren, die diese Unterschiede erkl\u00e4ren (DZKJ)\nDrop-out-Raten \u00fcber die Zeit zu ermitteln und die Gr\u00fcnde daf\u00fcr zu verstehen (DZKJ)\"}}]\n            }\n          <\/script>\n\n          <div class=\"accordion__content\">\n                          <div class=\"accordion-item  box box--accordion over launimation slideBottom\">\n                <button class=\"accordion-item__title\"\n                        aria-expanded=\"true\"\n                        aria-controls=\"accordion_69f2589a5c58d_0\"\n                        aria-label=\"Zeige den Inhalt an\">\n                    <span class=\"accordion-item__title-wrapper\">\n                      <span class=\"accordion-item__title-main h5\">Collaborating partners<\/span>\n                                          <\/span>\n                  <span class=\"icon-wrapper\"><\/span>\n                <\/button>\n\n                <div class=\"accordion-item__content-container\" id=\"accordion_69f2589a5c58d_0\">\n                  <div class=\"accordion-item__content\">\n                    \n                    <div class=\"accordion-item__content-text wysiwyg\">\n                      <p>Das Projekt wurde gemeinsam mit der Augenabteilung am St. Franziskus Hospital in M\u00fcnster und der Klinik f\u00fcr P\u00e4diatrische Rheumatologie und Immunologie in M\u00fcnster durchgef\u00fchrt. Der Verbund kooperierte prim\u00e4r mit 11 kinderrheumatologischen Zentren. Im Verlauf kamen noch etwa 180 nicht prim\u00e4r involvierte p\u00e4diatrisch- und internistisch-rheumatologische Einrichtungen und etwa 400 augen\u00e4rztlichen Einrichtungen hinzu.<\/p>\n<p><strong>Aktuelle Vorhaben<\/strong><\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong>Daten der ICON-Fr\u00fchkohorte werden derzeit genutzt, um<\/strong><\/p>\n<ul>\n<li>die Krankheitskosten der JIA zu sch\u00e4tzen (PAVE)<\/li>\n<li>die famili\u00e4re Belastung durch die Erkrankung zu untersuchen (PAVE)<\/li>\n<li>die Inanspruchnahme von und Zufriedenheit mit Versorgungsleistungen \u00fcber die Zeit zu analysieren (DZKJ)<\/li>\n<li>Verl\u00e4ufe von Gesundheits- und Risikoverhalten bei Jugendlichen mit juveniler idiopathischer Arthritis im Vergleich zu Kontrollen zu ermitteln (DZKJ)<\/li>\n<li>die Lebenszufriedenheit Jugendlicher mit JIA mit jener altersentsprechender Kontrollen zu vergleichen<\/li>\n<li>die emotionale Belastung und gesundheitsbezogene Lebensqualit\u00e4t von Kindern und Jugendlichen mit juveniler idiopathischer Arthritis im Krankheitsverlauf zu erfassen und assoziierte Faktoren zu ermitteln<\/li>\n<li>Unterschiede zwischen der Wahrnehmung der Krankheitsaktivit\u00e4t bei der JIA durch Kinder, Eltern und \u00c4rzte zu untersuchen und Faktoren zu identifizieren, die diese Unterschiede erkl\u00e4ren (DZKJ)<\/li>\n<li>Drop-out-Raten \u00fcber die Zeit zu ermitteln und die Gr\u00fcnde daf\u00fcr zu verstehen (DZKJ)<\/li>\n<\/ul>\n\n                                          <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n                      <\/div>\n        <\/div>\n          <\/div>\n  <\/section>\n\n\n\n\n  <section id=\"block_a84682b0383e9b9ca3ac39a98272fb72\" class=\"section cta  alignwide\">\n    <div class=\"container container--center\">\n\n      <div class=\"cta__wrapper bg bg--surface\">\n        <div class=\"cta__content\">\n                      <h2 class=\"cta__heading launimation slideBottom\">AG Minden<\/h2>\n          \n                      <div class=\"cta__desc wysiwyg launimation slideBottom\">Kinder- und Jugendrheumatologie<\/div>\n          \n          \n                      <div class=\"cta__ctas button-group\">\n              <a href=\"\/arbeitsgruppen\/kinder-und-jugendrheumatologie\/\" class=\"cta__button button button--arrow launimation slideBottom\" title=\"\" target=\"_self\"><span><\/span><\/a>            <\/div>\n                  <\/div><!-- content -->\n\n                  <div class=\"cta__image launimation fadeIn\">\n            <img decoding=\"async\" loading=\"lazy\" sizes=\"auto, \" src=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/12\/Minden_group_2019-150x100.jpg\" data-src=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/12\/Minden_group_2019-1024x683.jpg\" data-srcset=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/12\/Minden_group_2019-1920x1280.jpg 1920w, https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/12\/Minden_group_2019-1600x1067.jpg 1600w, https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/12\/Minden_group_2019-1366x911.jpg 1366w, https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/12\/Minden_group_2019-1024x683.jpg 1024w, https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/12\/Minden_group_2019-768x512.jpg 768w, https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/12\/Minden_group_2019-550x367.jpg 550w\" class=\"\" alt=\"DRFZ Kinder- und Jugendrheumatologie Arbeitsgruppe Minden\"  width=\"1024\"  height=\"683\">          <\/div>\n              <\/div><!-- wrapper -->\n\n    <\/div><!-- container -->\n  <\/section>\n\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"author":5,"featured_media":0,"template":"","programme-area-tax":[180],"supporter":[263],"working-group-tax":[252],"class_list":["post-16220","project","type-project","status-publish","hentry","programme-area-tax-programme-area-2","supporter-bmbf-en","working-group-tax-paediatric-rheumatology-and-health-services-research"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICON - DRFZ<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.drfz.de\/en\/forschungsprojekte\/icon\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ICON - DRFZ\" \/>\n<meta property=\"og:description\" content=\"Current projects Data from the ICON early cohort are currently being used to\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.drfz.de\/en\/forschungsprojekte\/icon\/\" \/>\n<meta property=\"og:site_name\" content=\"DRFZ\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/drfz.de\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-04-01T11:35:08+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/11\/0265bc75f81cee07e381d8975805d2a6.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@DRFZ_Berlin\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/forschungsprojekte\\\/icon\\\/\",\"url\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/forschungsprojekte\\\/icon\\\/\",\"name\":\"ICON - DRFZ\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/#website\"},\"datePublished\":\"2023-01-23T11:00:00+00:00\",\"dateModified\":\"2025-04-01T11:35:08+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/forschungsprojekte\\\/icon\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.drfz.de\\\/en\\\/forschungsprojekte\\\/icon\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/forschungsprojekte\\\/icon\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research Projects\",\"item\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/research-projects\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"ICON\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/\",\"name\":\"DRFZ\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/#organization\",\"name\":\"Deutsches Rheuma-Forschungszentrum\",\"url\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.drfz.de\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/drfz-footer-logo.svg\",\"contentUrl\":\"https:\\\/\\\/www.drfz.de\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/drfz-footer-logo.svg\",\"width\":1,\"height\":1,\"caption\":\"Deutsches Rheuma-Forschungszentrum\"},\"image\":{\"@id\":\"https:\\\/\\\/www.drfz.de\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/drfz.de\\\/\",\"https:\\\/\\\/x.com\\\/DRFZ_Berlin\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/deutsches-rheuma-forschungszentrum-berlin\",\"https:\\\/\\\/www.youtube.com\\\/channel\\\/UCf8nDuqpkWwcmCWmfSTkE3w\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"ICON - DRFZ","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.drfz.de\/en\/forschungsprojekte\/icon\/","og_locale":"en_US","og_type":"article","og_title":"ICON - DRFZ","og_description":"Current projects Data from the ICON early cohort are currently being used to","og_url":"https:\/\/www.drfz.de\/en\/forschungsprojekte\/icon\/","og_site_name":"DRFZ","article_publisher":"https:\/\/www.facebook.com\/drfz.de\/","article_modified_time":"2025-04-01T11:35:08+00:00","og_image":[{"width":1024,"height":1024,"url":"https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/11\/0265bc75f81cee07e381d8975805d2a6.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_site":"@DRFZ_Berlin","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.drfz.de\/en\/forschungsprojekte\/icon\/","url":"https:\/\/www.drfz.de\/en\/forschungsprojekte\/icon\/","name":"ICON - DRFZ","isPartOf":{"@id":"https:\/\/www.drfz.de\/en\/#website"},"datePublished":"2023-01-23T11:00:00+00:00","dateModified":"2025-04-01T11:35:08+00:00","breadcrumb":{"@id":"https:\/\/www.drfz.de\/en\/forschungsprojekte\/icon\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.drfz.de\/en\/forschungsprojekte\/icon\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.drfz.de\/en\/forschungsprojekte\/icon\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.drfz.de\/en\/"},{"@type":"ListItem","position":2,"name":"Research Projects","item":"https:\/\/www.drfz.de\/en\/research-projects\/"},{"@type":"ListItem","position":3,"name":"ICON"}]},{"@type":"WebSite","@id":"https:\/\/www.drfz.de\/en\/#website","url":"https:\/\/www.drfz.de\/en\/","name":"DRFZ","description":"","publisher":{"@id":"https:\/\/www.drfz.de\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.drfz.de\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.drfz.de\/en\/#organization","name":"Deutsches Rheuma-Forschungszentrum","url":"https:\/\/www.drfz.de\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.drfz.de\/en\/#\/schema\/logo\/image\/","url":"https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/10\/drfz-footer-logo.svg","contentUrl":"https:\/\/www.drfz.de\/wp-content\/uploads\/2024\/10\/drfz-footer-logo.svg","width":1,"height":1,"caption":"Deutsches Rheuma-Forschungszentrum"},"image":{"@id":"https:\/\/www.drfz.de\/en\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/drfz.de\/","https:\/\/x.com\/DRFZ_Berlin","https:\/\/www.linkedin.com\/company\/deutsches-rheuma-forschungszentrum-berlin","https:\/\/www.youtube.com\/channel\/UCf8nDuqpkWwcmCWmfSTkE3w"]}]}},"_links":{"self":[{"href":"https:\/\/www.drfz.de\/en\/wp-json\/wp\/v2\/project\/16220","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.drfz.de\/en\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/www.drfz.de\/en\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/www.drfz.de\/en\/wp-json\/wp\/v2\/users\/5"}],"version-history":[{"count":9,"href":"https:\/\/www.drfz.de\/en\/wp-json\/wp\/v2\/project\/16220\/revisions"}],"predecessor-version":[{"id":16493,"href":"https:\/\/www.drfz.de\/en\/wp-json\/wp\/v2\/project\/16220\/revisions\/16493"}],"wp:attachment":[{"href":"https:\/\/www.drfz.de\/en\/wp-json\/wp\/v2\/media?parent=16220"}],"wp:term":[{"taxonomy":"programme-area-tax","embeddable":true,"href":"https:\/\/www.drfz.de\/en\/wp-json\/wp\/v2\/programme-area-tax?post=16220"},{"taxonomy":"supporter","embeddable":true,"href":"https:\/\/www.drfz.de\/en\/wp-json\/wp\/v2\/supporter?post=16220"},{"taxonomy":"working-group-tax","embeddable":true,"href":"https:\/\/www.drfz.de\/en\/wp-json\/wp\/v2\/working-group-tax?post=16220"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}