Research project within the Leibniz Collaborative Excellence Program
Published: 2. Januar 2021
Who we are
Our group at the Deutsches Rheuma-Forschungszentrum, an institute of the Leibniz Association, (AG Melchers) pursues a research project within the Leibniz Collaborative Excellence Program (Leibniz Association) in collaboration with the:
- Max Planck Institute for Infection Biology in Berlin (MPIIB) (AG Kaufmann)
- Department of Dermatology at the Medical University at the AKH in Vienna (DIAID) (AG Stingl)
- Leibniz Forschungszentrum in Borstel, (AG Scheible)
- Helmholtz Institute for RNA-based Infection Research in Würzburg (HIRI) (AG Vogel) and the
- Faculty of Biological Sciences of the University of Leeds (AG Richter).
What we are doing
We intend to define cellular and molecular properties of quiescent and of activated hematopoietic stem cells (HSC). As quiescent, non-dividing cells, HSC survive in small numbers life-long in bone marrow of vertebrates. This cellular status of HSC can provide long-term residence for latent infections, such as Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis. Other HSC continuously regenerate all cells of blood and of the innate and adaptive immune system by proliferation and differentiation. HSC can respond to infection and stress by accelerated, selective differentiation to defense cells.
Who we are looking for
We are calling for a motivated, independent and responsible person (m/f/div) on short or mid-time period into our working group (DRFZ, Berlin) with the possibility of working part of the time in the laboratory of one of our collaborative partners.
What we offer
We offer appointments on short-term (3-6 months) or Master work (1 year) levels, to whom are interested in joining us in this intriguing and challenging endeavor.
The DRFZ is an equal opportunity employer, and strongly encourages applications from all members of under-represented groups.
Individuals with disabilities will be given priority, if qualified accordingly.
For more information, you can find us in the Deutsches Rheuma-Forschungszentrum, Charitéplatz 1, 10117 Berlin, Germany, or contact Professor Dr. Fritz Melchers.
Tel.: +49 30 28460260, e-mail: email@example.com