Research is a continuous and lengthy process. Developments in the field of rheumatology and immunology have been driven forward with great commitment for many decades and have already achieved significant progress. Although we cannot offer you any direct treatments at the DRFZ, we are working hard to make rheumatism curable. Your well-being is important to us and we are committed to developing innovative solutions for the future.
There are many new developments at the Leibniz Institute German Center for Rheumatology Research. Following a change in the institute’s management, the DRFZ’s image has been refreshed and a new short film about the DRFZ’s research work is now available. The motto ‘Rheumatic diseases in focus—shaping health’ underlines the institute’s direction in the coming years: findings from rheumatology research will be specifically translated into concrete improvements for people’s health.
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Flow & mass cytometryReal-time analysis of cell populations
Robotics – increasing efficiency through automation in research
Imaging technologiesPrecise insights into cell processes
Focus on immune cells: advanced technologies at the DRFZ
The DRFZ is revolutionizing immune cell research with innovative technologies. These make it possible to observe, identify and specifically isolate immune cells in their natural tissue environment. After isolation, the cells are comprehensively analyzed in in-depth molecular and functional studies. This creates a new understanding of the complex interactions in the immune system.
Imaging technologies play a central role in biological research by enabling the visualization of cellular and subcellular structures at the highest resolution. Through advanced microscopy techniques, such as confocal and fluorescence microscopy, researchers can observe dynamic processes in living cells and analyze their interactions in real time. These precise visualizations are crucial for deepening the understanding of diseases and identifying new therapeutic targets.
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Flow and mass cytometry provide powerful methods for analyzing cell populations in real time by examining individual cells based on their physical and chemical properties. These technologies allow for the simultaneous measurement of multiple markers, delivering detailed information about cell diversity, activation, and state. This is especially important in immunology and cancer research, where understanding heterogeneous cell populations is critical for developing new therapies.
Robotic solutions are revolutionizing research at the DRFZ by increasing the efficiency and reproducibility of experiments. Automated systems take over routine tasks such as pipetting and sample preparation, minimizing human error and reducing processing times. These technologies allow researchers to focus on more complex analyses and creative questions, ultimately leading to faster and more accurate research outcomes.
Hardenberg JB, Hinz RM, Pigorsch M, Uhrig A, Müller-Redetzky H, Nee J, Schroeder T, Witzenrath M, Trost U, Zickler D, Hunsicker O, Weiss B, Weber-Carstens S, Spies CM, Tampe B, Borgstedt R, Abu-Tair M, Zarbock A, Strauß C, Schenk H, Hildebrand U, Wedel D, Balzer F, Eckardt KU, Enghard P.
