Health Services ResearchProf. Dr. Angela Zink
Health Services Research
Prof. Dr. Angela Zink
Angela Zink is in charge of the thematic orientation of the epidemiological research at the DRFZ since its foundation in 1991. Since 2003, she has been professor for rheumatism epidemiology at the Clinic for Rheumatology and Clinical Immunology of the Charité University Hospital Berlin.
Angela Zink is in charge of the thematic orientation of the epidemiological research at the DRFZ. She has been the head of the epidemiology unit (formerly: epidemiology research unit) since its foundation in 1991. This research unit establishes extensive patient cohorts, which are used to visualise the successes and shortcomings in the treatment of rheumatic patients. Since 2003, she has additionally been professor for rheumatism epidemiology at the Clinic for Rheumatology and Clinical Immunology of the Charité University Hospital Berlin. She has been deputy scientific director of the DRFZ since 1997.
Angela Zink started her epidemiological research activities at the German Federal Health Department (today Robert Koch Institute) with investigations concerning the health care of rheumatic patients. Later on, she conducted research projects on infant mortality, child accidents, cultural determinants of subjective disease perception and the evaluation of new health care services for children suffering from chronic diseases. She was actively involved in the organisation of the study course “Social medicine for sociologists” at the Free University of Berlin and has been engaged in the social medical and epidemiological education of medical professionals for many years.
Within the rheumatism epidemiology research, she is especially interested in issues concerning the quality and appropriateness of health care, including the identification of deficits and trends in the treatment process, the prognosis of rheumatic diseases in childhood and adulthood, the testing of new therapeutic methods as well as the long-term safety of new drugs. She places special focus on the interaction of biological, clinical and social factors, which can only be examined in a highly diversified interdisciplinary team.
In 2001, Angela Zink initiated one of the world’s major biologics registers, in which nearly 18,000 patients are now being observed. The results obtained from this register provide a solid basis to assess the risks and opportunities of the widespread application of new therapies on unselected patients. Furthermore, the study group around Angela Zink has always been actively involved in testing new therapeutic methods in randomised clinical trials in close cooperation with the rheumatologists of the Charité.
Angela Zink has been author or co-author of roughly 180 original publications and 60 reviews and book chapters. She is a member of the advisory board of the German Society for Rheumatology, co-publisher of the Journal of Rheumatology, deputy spokeswoman of the Competence Network Rheumatology and spokeswoman of the health care research unit, member of the Executive Committee of EULAR (European League against Rheumatism) and chairwoman of the EULAR Standing Committee on Epidemiology and Health Services Research.
For her research, she has received the Federal Cross of Merit, the rheo Progress Prize of the German Rheumatism League, the Francois Blondel Medal of the City of Aachen and, together with the core documentation team, the Kussmaul Medal of the German Society for Rheumatology.
CV and Key Publications
- Since 2003 Professor of Epidemiology of the Rheumatic Diseases, Charité University Medicine Berlin
- Since 1996 Deputy Scientific Director of the German Rheumatism Research Centre, Berlin (DRFZ)
- Since 1991 Head of the DRFZ Programme Area Epidemiology
- 1985 – 1991 Head of Department of Epidemiology and Health Services Research at GSD Health Systems Research Ltd., Berlin
- 1977 – 1985 Research and Teaching in Epidemiology and Medical Sociology in various Research Institutes and the Free University of Berlin
- 1998 Habilitation in Epidemiology (Charité Berlin)
- 1984 PhD in Medical Sociology (Free University of Berlin)
- 1972 – 1977 Studies of Sociology, Psychology and Economics; Diploma from Free University of Berlin in 1977
- From 2018 Member of the Scientific Committee of FOREUM (Foundation for Research in Rheumatology)
- Since 2013 Member of Leibniz Prize Jury
- Since 2012 Faculty/host of annual EULAR Advanced Epidemiology Course
- Since 2006 Member of several EULAR task forces and working groups
- Since 2005 Editor Zeitschrift fuer Rheumatologie
- Since 2005 Member of several committees for professorships at the Charité University Medicine
- Since 2002 Member of the Advisory Board of the German Society for Rheumatology
- Since 2000 Speaker of Health Services Research Section of Competence Network Rheumatology
- 2009 – 2012 Chair / past chair of Standing Committee on Epidemiology of EULAR (European League against Rheumatism)
- 2006 – 2011 Speaker (2006-07) and deputy speaker (2008-2011) of German Competence Network Rheumatology
- Honorary member of EULAR
- American College for Rheumatology
- German Society for Rheumatology
- German Society for Social Medicine and Prevention
- German Society for Epidemiology
- German Society for Medical Sociology
- German Network Healthcare Research
- 2016 Carol-Nachman-Medal
- 2010 Rheo Price of Progress
- 2010 Francois-Blondel-Medal
- 1999 Federal Cross of Merit
- 1997 Tosse Prize
- 2011 – 2018 National Database of the Arthritis Centres (unconditional grant from industry consortium, 900,000 EUR)
- 2015 – 2018 PROCLAIR and Metarthros (BMBF: 685.000 EUR)
- 2011 – 2018 RABBIT – Biologics Register in RA (unconditional grant from industry consortium, jointly with Strangfeld, 50% of total = 3,500,000 EUR)
- Redeker I, Hoffmann F, Callhoff J, Haibel H, Sieper J, Zink A, Poddubnyy D. Determinants of psychological well-being in axial spondyloarthritis: an analysis based on linked claims and patient-reported survey data. Ann Rheum Dis 2018 Mar 10 (online first)
- Albrecht K, Luque Ramos A, Hoffmann F, Redeker I, Zink A. High prevalence of diabetes in patients with rheumatoid arthritis: Results from a questionnaire survey linked to claims data. Rheumatology (Oxford). 2018; 57(2):329-336
- Baganz L, Richter A, Kekow J, Bussmann A, Krause A, Stille C, Listing J, Zink A, Strangfeld A. Long-term effectiveness of tocilizumab in patients with rheumatoid arthritis, stratified by number of previous treatment failures with biologic agents: results from the German RABBIT cohort. Rheumatol Int 2018; 38(4):579-587
- Albrecht K, Huscher D, Buttgereit F, Aringer M, Hoese G, Ochs W, Thiele K, Zink A. Long-term glucocorticoid treatment in patients with polymyalgia rheumatica, giant cell arteritis, or both diseases: results from a national rheumatology database. Rheumatol Int. 2018 Apr;38(4):569-577.
- Meissner Y, Richter A, Manger B, Tony HP, Wilden E, Listing J, Zink A, Strangfeld A. Serious adverse events and the risk of stroke in patients with rheumatoid arthritis: results from the German RABBIT cohort. Ann Rheum Dis 2017; 76(9):1583-1590.
- Strangfeld A, Richter A, Siegmund B, Herzer P, Rockwitz K, Demary W, Aringer M, Meissner Y, Zink A, Listing J. Risk for lower intestinal perforations in patients with rheumatoid arthritis treated with tocilizumab in comparison to treatment with other biologic or conventional synthetic DMARDs. Ann Rheum Dis 2017; 76(3):504-510.
- Callhoff J, Luque Ramos A, Zink A, Hoffmann F, Albrecht K. The Association of Low Income with Functional Status and Disease Burden in German Patients with Rheumatoid Arthritis: Results of a Cross-sectional Questionnaire Survey Based on Claims Data. J Rheumatol. 2017;44(6):766-772
- Albrecht K, Richter A, Callhoff J, Huscher D, Schett G, Strangfeld A, Zink A. Body mass index distribution in rheumatoid arthritis: a collaborative analysis from three large German rheumatoid arthritis databases. Arthritis Res Ther 2016; 18:149
- Callhoff J, Luque Ramos A, Zink A, Hoffmann F, Albrecht K. The Association of Low Income with Functional Status and Disease Burden in German Patients with Rheumatoid Arthritis: Results of a Cross-sectional Questionnaire Survey Based on Claims Data. J Rheumatol 2017; 44(6):766-772.
- Albrecht K, Callhoff J, Buttgereit F, Straub RH, Westhoff G, Zink A. Association Between the Use of Oral Contraceptives and Patient-Reported Outcomes in an Early Arthritis Cohort. Arthritis Care Res (Hoboken ) 2016;68(3):400-405.