IMI RTCure – Rheuma Tolerance for Cure

The European consortium RTCure – Rheuma Tolerance for Cure aims to develop therapies for patients in the earliest stages of rheumatoid arthritis (RA) and for people with a high risk of developing this disease.

The network is to develop new methods for biomonitoring the course of the disease and the treatment response. In addition, therapeutic approaches to restore immune tolerance are to be established that prevent or stop attacks by the immune system on the joints and at the same time ensure that the immune system remains capable of fending off infections. The long-term goal is to prevent or reverse the onset of RA and to cure patients in early stages of the disease.

The DRFZ leads work package 3 “Mechanisms of Immune Tolerance“ (Andreas Radbruch and Hyun-Dong Chang) and contributes to different additional work-packages.