Prof. Dr. Fritz Melchers †

Since 2017rnSenior Scientist and Group Leader, DRFZrnrn2008 – 2016rnMax Planck Fellowrnrn2003 – 2007rnSenior Research Group Leader, Max Planck Institute for Infection Biology, Berlinrnrn1981 – 2001rnDirector, Basel Institute for Immunology, Basel, Switzerlandrnrn1970 – 1980rnPermanent Member, Basel Institute for Immunology, Basel, Switzerlandrnrn1970 – 1971rnVisiting Scientist, Department of Genetics, Stanford University Medical Schoolrnrn1970rnVisiting Scientist, Weizmann Institute, Rehovot, Israelrnrn1970rnSenior Research Assistant, Max Planck Institute for Molecular Genetics, Berlinrnrn1968 – 1969rnPostdoctoral Fellow, Max Planck Institute for Molecular Genetics, Berlinrnrn1965 – 1967rnResearch Associate, Salk Institute for Biological Studies, La Jolla, CA, USA (Fulbright)rnrn1971rnDr. rer. nat. habil., Venia legendi, University of Freiburg i.Br., Faculty of Biologyrnrn1964rnPh.D. (Dr. rer. nat.), University of Cologne, Germanyrnrn1961rnDipl. chem., University of Cologne, German

2010 – 2018rnTuberculosis Vaccine Initiative, Amsterdamrnrn2003 – 2010rnMember and Vice-President, University Council Hannover Medical School, Germanyrnrn2002 – 2014rn4-Antibody GmbH, Basel, Switzerland, Co-founderrnrn1998 – 2001rnPresident, IUIS (International Union of Immunological Societies)rnrn1996 – 2003rnMember “Universitätsrat“, University of Basel, Switzerlandrnrn1993 – 1996rnNationaler Forschungsrat der Schweiz, Bern, Switzerlandrnrn1992 – 1999rnMax Delbrück Center for Molecular Medicine, Berlin-Buch, Germanyrnrn1986 – 1996rnPaul Ehrlich Foundation, Frankfurt am Main, Germanyrnrn1986 – 2001rnDeutsches Rheuma-Forschungszentrum, Berlin, Germany

Academia EuropearnrnLeopoldinarnrnNorwegian Academy of Science and LettersrnrnSwiss Academy of Medical SciencesrnrnAmerican Academy for Arts and SciencernrnAustrian Academy of Sciences

2018rnLeibniz-Chair, Leibniz Associationrnrn2017rnCothenius Medal, Leopoldinarnrn2009rnM.D.h.c. Medical University Innsbruck, Austriarnrn2007rnNovartis Prize for Basic Immunologyrnrn2007rnM.D.h.c. University of Würzburg, Germanyrnrn2006rnPh.D.h.c. University of Leipzig, Germanyrnrn2003rnM.D.h.c., University of Erlangen- Nuremberg, Germanyrnrn2002rnGaikokujin Chomei Kenkyu-shu (Eminent Scientist) Award of the Japanese Society for the Promotion of Science (JSPS) at the University of Tokyo School of Medicinernrn2002rnExternal Scientific Member, Max Planck-Institute for Infection Biology, Berlinrnrn2002rnEmil von Behring Preis, Marburg, Germanyrnrn2001rnHonorary Professor, Medical Faculty, University of Innsbruck, Austriarnrn2000rnrnSan Marino Prize 2000rnrn1997rnMax Delbrück Medal, MDC, Berlin, Germanyrnrn1996rnRobert-Koch Prize, Bonn, Germanyrnrn1996rnPrausnitz-Medaille, Collegium Internationale Allergologicum (CIA), Viennarnrn1995rnBundesverdienstkreuz 1. Klasse der Bundesrepublik Deutschlandrnrn1994rnPh.D.h.c., Medical College, Thomas Jefferson University, Philadelphia, USArnrn1990rnM.D.h.c., University of Turku, Finlandrnrn1988rnCommendatore dell Ordine di Sant’ Agata, San Marinornrn1978rnHonorary Professor, Faculty of Biology, Heidelberg University, Germany

1. Kawano Y, Petkau G, Stehle C, Durek P, Heinz GA, Tanimoto K, Karasuyama H, Mashreghi MF, Romagnani C, Melchers F. Stable lines and clones of long-term proliferating normal, genetically unmodified murine common lymphoid progenitors. Blood. 2018 May 3;131(18):2026-2035.rnrn2. Petkau G, Kawano Y, Wolf I, Knoll M, Melchers F. MiR221 promotes precursor B-cell retention in the bone marrow by amplifying the PI3K-signaling pathway in mice. Eur J Immunol. 2018 Mar 5. doi: 10.1002/eji.201747354.rnrn3. Tornack J, Kawano Y, Garbi N, Hämmerling GJ, Melchers F, Tsuneto M. Flt3 ligand-eGFP-reporter expression characterizes functionally distinct subpopulations of CD150+ long-term repopulating murine hematopoietic stem cells. Eur J Immunol. 2017 Sep;47(9):1477-1487.rnrn4. Wolf I, Bouquet C, Naumann F, Melchers F. Generation of precursor, immature, and mature murine B1-cell lines from c-myc/bcl-xL-overexpressing pre-BI cells. Eur J Immunol. 2017 May;47(5):911-920. doi: 10.1002/eji.201746937. Epub 2017 Apr 6.rnrn5. Tornack J, Reece ST, Bauer WM, Vogelzang A, Bandermann S, Zedler U, Stingl G, Kaufmann SH, Melchers F. Human and Mouse Hematopoietic Stem Cells Are a Depot for Dormant Mycobacterium tuberculosis. PLoS One. 2017 Jan 3;12(1):e0169119. doi: 10.1371/journal.pone.0169119. eCollection 2017.rnrn6. Wolf I, Bouquet C, Melchers F. cDNA-library testing identifies transforming genes cooperating with c-myc in mouse pre-B cells. Eur J Immunol. 2016 Nov;46(11):2555-2565.rnrn7. Kawano Y, Petkau G, Wolf I, Tornack J, Melchers F. IL-7 and immobilized Kit-ligand stimulate serum- and stromal cell-free cultures of precursor B-cell lines and clones. Eur J Immunol. 2017 Jan;47(1):206-212. doi: 10.1002/eji.201646677. Epub 2016 Nov 11.rnrn8. Kajikhina K, Melchers F, Tsuneto M. Chemokine polyreactivity of IL7Rα+CSF-1R+ lympho-myeloid progenitors in the developing fetal liver. Sci Rep. 2015 Aug 3;5:12817.rnrn9. Funakoshi S, Shimizu T, Numata O, Ato M, Melchers F, Ohnishi K. BILL-cadherin/cadherin-17 contributes to the survival of memory B cells. PLoS One. 2015 Jan 22;10(1):e0117566. doi: 10.1371/journal.pone.0117566. eCollection 2015.rnrn10.Knoll M, Simmons S, Bouquet C, Grün JR, Melchers F. miR-221 redirects precursor B cells to the BM and regulates their residence. Eur J Immunol. 2013 Sep;43(9):2497-506. doi: 10.1002/eji.201343367. Epub 2013 Jul 8