Prof. Dr. med. Thomas Dörner

Scientific Background

Scientific Career

1991
MD Thesis, Charite/Humboldt University Berlin

1996 – 1998
DFG-Postdoctoral Fellowship, Univ. of Texas Southwestern MC Dallas, TX., USA

1998
Habilitation, Charite/Humboldt University Berlin

2004
C3 Professorship, Ludwig Maximilian University Munich

2009 – 2019
W2-S Professorship, Stifterverband für die Dt. Wissenschaft/Charite, Universitäsmedizin Berlin

2019
W2 Professorship, Charite Universitätsmedizin Berlin

Education

1990
Medical School; Humboldt University/Charité Berlin

1991 – 1995
Training Internal Medicine/board certification Internal medicine; Dept. Rheumatology & Clin. Immunology/Charité Berlin

2000
Board certification Rheumatology; Dept. Rheumatology & Clin. Immunology/Charité Berlin

2006
Board certification Hemostaseology, Institute of Transfusion Medicine and Immune Hematology Charite

2010
Board certification Transf. Medicine; Institute of Transfusion Medicine and Immune Hematology Charite

Professional Activities

1990 – 1995
Residency Dept. Medicine, Charité Universitätsmedizin Berlin, Germany

1996 – 1998
Post-Doc, University of Texas Southwestern Medical Center at Dallas, TX. USA

2000 – 2003
Head Day Care Clinic, Dept. Medicine/Rheumatology and Clinical Immunology, Charité

2004
Professor of Rheumatology/Head Rheumatology at Ludwig Maximilian University Munich

2004 – 2009
Clinical Hemostaseology, Institute of Transfusion Medicine and Immune Hematology

Since 2004
Lead instructor “Interdisciplinary 24/7 Coagulation Service” Charite

Since 2004
Liaison Group Leader „B cell Memory“ at DRFZ Berlin

Since 2009
Professorship Innovative Therapies for Autoimmune Diseases; Clinical Hemostaseology, Department Medicine/Rheumatology and Clinical Immunology

Board member: FOREUM; SLEuro; Lupus Academy. Associate Editor: Lupus: Science and Medicine; Annals of Rheumatic Diseases, European Journal of Immunology, Lupus, Z.f.Rheumatologie

Society Membership

Member of the German Society of Rheumatology; Henry Kunkel Society (USA); Board Member of The Lupus Academy; Berlin Chamber of Physicians/Examination Board; EULAR Scientific Committee 2016-20; FOREUM scientific board member (since 2024)

Board Member Rheumaliga Berlin e.V.; Deutsche Gesellschaft für Rheumatologie (Spokesperson Laborkommission)

Fellowship and Awards

2023
EULAR Honorary Award

2010
Randy Fischer Prize (NIH)

2003
Prize der Wolfgang-Schultze-Foundation/Deutsche Rheumaliga

2000
Rudolf-Schoen Prize (DGRh)

1998
Senior Scholar Award American College of Rheumatology

1996 – 1998
DFG Scholarship Post- Doc, University of Texas SW at Dallas, TX

1991
Travel Award DFG 57th ACR Meeting San Antonio, TX

TOP PUBLICATIONS

Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response Odendahl, M., Mei, H., Hoyer, B.F., Jacobi, A.M., Hansen, A., Muehlinghaus, G., Berek, C., Hiepe, F., Manz, R., Radbruch, A., and Dorner, T. (2005). Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response. Blood 105, 1614-1621.

Splenic proliferative lymphoid nodules distinct from germinal centers are sites of autoantigen stimulation in immune thrombocytopenia Daridon, C., Loddenkemper, C., Spieckermann, S., Kuhl, A.A., Salama, A., Burmester, G.R., Lipsky, P.E., and Dorner, T. (2012). Splenic proliferative lymphoid nodules distinct from germinal centers are sites of autoantigen stimulation in immune thrombocytopenia. Blood 120, 5021-5031.

Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients Rincon-Arevalo, H., Choi, M., Stefanski, A.L., Halleck, F., Weber, U., Szelinski, F., Jahrsdorfer, B., Schrezenmeier, H., Ludwig, C., Sattler, A., et al. (2021). Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients. Sci Immunol. 2021 Jun 15;6(60):eabj1031. doi: 10.1126/sciimmunol.abj1031. PMID: 34131023.

Plasmablast-like Phenotype Among Antigen-Experienced CXCR5–CD19low B Cells in Systemic Lupus Erythematosus Szelinski, F., Stefanski, A.L., Schrezenmeier, E., Rincon-Arevalo, H., Wiedemann, A., Reiter, K., Ritter, J., Lettau, M., Dang, V.D., Fuchs, S., et al. (2022). Plasmablast-like Phenotype Among Antigen-Experienced CXCR5-CD19(low) B Cells in Systemic Lupus Erythematosus. Arthritis Rheumatol 74, 1556-1568.

Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow Ferreira-Gomes M, Chen Y, Durek P, Rincon-Arevalo H, Heinrich F, Bauer L, Szelinski F, Guerra GM, Stefanski AL, Niedobitek A, Wiedemann A, Bondareva M, Ritter J, Lehmann K, Hardt S, Hipfl C, Hein S, Hildt E, Matz M, et al. Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow. Nat Commun. 2024 May 17;15(1):4182. doi: 10.1038/s41467-024-48570-0.

Dysregulation of immune checkpoint molecules as a characteristic of autoimmune congenital heart block Stefanski AL, Rincon-Arevalo H, Dressler-Steinbach I, Nomovi N, Mackert A, Aue A, Ritter J, Wiedemann A, Szelinski F, Schrezenmeier E, Kühl AA, Lino AC, Henrich W, Dörner T (2024). Dysregulation of immune checkpoint molecules as a characteristic of autoimmune congenital heart block. Ann Rheum Dis. 83(11):1598-1600. doi: 10.1136/ard-2024-226176

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AG Dörner

Scientific Background

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