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Prof. Dr. med. Thomas Dörner

Programmbereich 4, PB 4 – Translationale Rheumatologie

Gruppenleitung: B-Zell Gedächtnis

Liaisonarbeitsgruppe mit Charité - Rheumatologie und Klinische Immunologie

+49 (0)30 450 525 241

thomas.doerner@charite.de

Scientific Background

1991rnMD Thesis, Charite/Humboldt University Berlinrnrn1996 – 1998rnDFG-Postdoctoral Fellowship, Univ. of Texas Southwestern MC Dallas, TX., USArnrn1998rnHabilitation, Charite/Humboldt University Berlinrnrn2004rnC3 Professorship, Ludwig Maximilian University Munichrnrn2009 – 2019rnW2-S Professorship, Stifterverband für die Dt. Wissenschaft/Charite, Universitäsmedizin Berlinrnrn2019rnW2 Professorship, Charite Universitätsmedizin Berlin

1990rnMedical School; Humboldt University/Charité Berlinrnrn1991 – 1995rnTraining Internal Medicine/board certification Internal medicine; Dept. Rheumatology u0026amp; Clin. Immunology/Charité Berlinrnrn2000rnBoard certification Rheumatology; Dept. Rheumatology u0026amp; Clin. Immunology/Charité Berlinrnrn2006rnBoard certification Hemostaseology, Institute of Transfusion Medicine and Immune Hematology Chariternrn2010rnBoard certification Transf. Medicine; Institute of Transfusion Medicine and Immune Hematology Charite

1990 – 1995rnResidency Dept. Medicine, Charité Universitätsmedizin Berlin, Germanyrnrn1996 – 1998rnPost-Doc, University of Texas Southwestern Medical Center at Dallas, TX. USArnrn2000 – 2003rnHead Day Care Clinic, Dept. Medicine/Rheumatology and Clinical Immunology, Charitérnrn2004rnProfessor of Rheumatology/Head Rheumatology at Ludwig Maximilian University Munichrnrn2004 – 2009rnClinical Hemostaseology, Institute of Transfusion Medicine and Immune HematologyrnrnSince 2004rnLead instructor “Interdisciplinary 24/7 Coagulation Service” ChariternrnSince 2004rnLiaison Group Leader „B cell Memory“ at DRFZ BerlinrnrnSince 2009rnProfessorship Innovative Therapies for Autoimmune Diseases; Clinical Hemostaseology, Department Medicine/Rheumatology and Clinical ImmunologyrnrnBoard member: FOREUM; SLEuro; Lupus Academy. Associate Editor: Lupus: Science and Medicine; Annals of Rheumatic Diseases, European Journal of Immunology, Lupus, Z.f.Rheumatologie

Member of the German Society of Rheumatology; Henry Kunkel Society (USA); Board Member of The Lupus Academy; Berlin Chamber of Physicians/Examination Board; EULAR Scientific Committee 2016-20; FOREUM scientific board member (since 2024)rnrnBoard Member Rheumaliga Berlin e.V.; Deutsche Gesellschaft für Rheumatologie (Spokesperson Laborkommission)

2023rnEULAR Honorary Awardrnrn2010rnRandy Fischer Prize (NIH)rnrn2003rnPrize der Wolfgang-Schultze-Foundation/Deutsche Rheumaligarnrn2000rnRudolf-Schoen Prize (DGRh)rnrn1998rnSenior Scholar Award American College of Rheumatologyrnrn1996 – 1998rnDFG Scholarship Post- Doc, University of Texas SW at Dallas, TXrnrn1991rnTravel Award DFG 57th ACR Meeting San Antonio, TX

TOP 5 PUBLICATIONS

Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response Odendahl, M., Mei, H., Hoyer, B.F., Jacobi, A.M., Hansen, A., Muehlinghaus, G., Berek, C., Hiepe, F., Manz, R., Radbruch, A., and Dorner, T. (2005). Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response. Blood 105, 1614-1621.
Splenic proliferative lymphoid nodules distinct from germinal centers are sites of autoantigen stimulation in immune thrombocytopenia Daridon, C., Loddenkemper, C., Spieckermann, S., Kuhl, A.A., Salama, A., Burmester, G.R., Lipsky, P.E., and Dorner, T. (2012). Splenic proliferative lymphoid nodules distinct from germinal centers are sites of autoantigen stimulation in immune thrombocytopenia. Blood 120, 5021-5031.
Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients Rincon-Arevalo, H., Choi, M., Stefanski, A.L., Halleck, F., Weber, U., Szelinski, F., Jahrsdorfer, B., Schrezenmeier, H., Ludwig, C., Sattler, A., et al. (2021). Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients. Sci Immunol. 2021 Jun 15;6(60):eabj1031. doi: 10.1126/sciimmunol.abj1031. PMID: 34131023.
Plasmablast-like Phenotype Among Antigen-Experienced CXCR5–CD19low B Cells in Systemic Lupus Erythematosus Szelinski, F., Stefanski, A.L., Schrezenmeier, E., Rincon-Arevalo, H., Wiedemann, A., Reiter, K., Ritter, J., Lettau, M., Dang, V.D., Fuchs, S., et al. (2022). Plasmablast-like Phenotype Among Antigen-Experienced CXCR5-CD19(low) B Cells in Systemic Lupus Erythematosus. Arthritis Rheumatol 74, 1556-1568.
Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow Ferreira-Gomes M, Chen Y, Durek P, Rincon-Arevalo H, Heinrich F, Bauer L, Szelinski F, Guerra GM, Stefanski AL, Niedobitek A, Wiedemann A, Bondareva M, Ritter J, Lehmann K, Hardt S, Hipfl C, Hein S, Hildt E, Matz M, et al. Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow. Nat Commun. 2024 May 17;15(1):4182. doi: 10.1038/s41467-024-48570-0.

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