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Regenerative Rheumatology

Program area 3

This programme area tries to find ways to regenerate tissue that has been destroyed by chronic degenerative diseases. The aim of the programme area is to gain a better understanding of the biology of cartilage-forming cells, and to influence cartilage formation in such a way that stable cartilage is rebuilt in affected joints in the long-term. Therapeutic oligonucleotides play an important role in this process: their suitability for the manipulation of chondrocytes and their precursors will be tested in animal models.