Home Research Pathophysiology of Rheumatic Inflammation

Pathophysiology of Rheumatic Inflammation

Program area 1

This programme area is investigating the causes of chronic rheumatic inflammation. Central questions are: how are these diseases initiated and what maintains them? How can they be cured in a targeted and definitive way? The research goal is therefore to design selective and curative therapies. In order to be able to use these therapies effectively, researchers are also developing prognostic biomarkers to reliably assess the course of the disease and the response to a specific form of therapy.

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Baumgrass lab

Regulation of cytokine expression in different T cell subsets
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Kallinich lab

Understanding chronic inflammation in the developing children
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Kruglov lab

Significance of immune system, cytokines and microbiota interplay for the development of chronic inflammation
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Chang lab

How does the intestinal microbiota influence chronic inflammation and cancer?
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Kubagawa lab

Better understanding of structure / function relationship of newly identified IgM Fc receptor
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Melchers lab

We intend to define molecular, cellular and functional properties of quiescent and of activated hematopoietic stem cells.
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Radbruch lab

Immunological memory is a driver of rheumatic inflammation
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Thurley lab

Understanding the complex relationships among immune cells with mathematical tools
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Tokoyoda lab

Maintenance of memory lymphocytes in protective and auto-reactive immunological memory
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Buttgereit lab

How do immune cells adapt to oxygen and nutrient deficiencies in inflamed tissue?
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Diefenbach lab

Development and function of the innate immune system
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Dörner lab

Immunomodulatory approaches targeting autoreactive B lineage cells while leaving protective B memory intact
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Hauser lab

We aim to understand the dynamic interactions of immune cells in the tissue context
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Hegazy lab

Host-Microbiota interactions shape intestinal inflammation
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Hiepe lab

New ways of approaching treatment of autoimmune diseases
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Hutloff lab

How dysregulated T cell / B cell interaction drives autoimmunity
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Niesner lab

We develop technologies for intravital imaging and live cell imaging to achieve new insights into chronic inflammatory processes
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Polansky-Biskup lab

How the structure of the genome shapes the immune system in health and disease
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Romagnani lab

Identifying innate signals initiating and perpetuating chronic inflammation
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Triantafyllopoulou lab

Macrophage biology and innate networks in chronic inflammatory diseases
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Worm lab

Novel therapeutic approaches of type I-allergy by immunomodulation