Home Research Pathophysiology of Rheumatic Inflammation

Pathophysiology of Rheumatic Inflammation

Program area 1

This programme area is investigating the causes of chronic rheumatic inflammation. Central questions are: how are these diseases initiated and what maintains them? How can they be cured in a targeted and definitive way? The research goal is therefore to design selective and curative therapies. In order to be able to use these therapies effectively, researchers are also developing prognostic biomarkers to reliably assess the course of the disease and the response to a specific form of therapy.

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Baumgrass lab

Regulation of cytokine expression in different T cell subsets
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Kruglov lab

Interaction of immune system and microbiota in chronic inflammation
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Chang lab

How does the intestinal flora influence chronic inflammation and cancer?
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Kubagawa lab

On the forefront of the defense system
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Melchers lab

How do antibody-producing B-lymphocytes develop from haematopoietic stem cells?
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Radbruch lab

Immunological memory as driver of rheumatic inflammation
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Thurley lab

Understanding the complex relationships among immune cells with mathematical tools
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Tokoyoda lab

Maintenance of memory lymphocytes in protective and auto-reactive immunological memory
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Buttgereit lab

How do immune cells adapt to oxygen and nutrient deficiencies in inflamed tissue?
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Diefenbach lab

Development and function of the innate immune system
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Dörner lab

Innovative insights into B Cell Memory with impact on protective and autoreactive immunity
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Hauser lab

Investigating the interaction of immune cells in living tissue
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Hegazy lab

Intestinal flora can cause chronic inflammation
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Hiepe lab

On new ways against autoimmune diseases
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Hutloff lab

When T cell / B cell crosstalk fails
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Niesner lab

We develop technologies for intravital imaging and live cell imaging to achieve new insights into chronic inflammatory processes
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Polansky-Biskup lab

How the structure of the genome shapes the immune system in health and disease
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Romagnani lab

Identifying innate signals initiating and perpetuating chronic inflammation
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Triantafyllopoulou lab

Innate Immunity in Rheumatic Diseases
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Worm lab

Novel therapeutic approaches of type I-allergy by immunomodulation