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News
- Wegbereiter der Stammzelltherapie zur Behandlung von Autoimmunerkrankungen zu Gast am DRFZ
- Fortschritte beim Sjögren-Syndrom: Erwerbstätig trotz „Rheuma“ der Speichel- und Tränendrüsen
- New – DRFZ Young Talents Fellowship
- 2nd German Mass Cytometry User Forum finished
- Kurzvortrag im Futurium: Rudolf Virchows Traum vollenden – Einzelzell-Medizin
- Depressive Zeichen bei Wirbelsäulenleiden: Studie zur Axialen Spondyloarthritis ausgezeichnet
- DRFZ nach Evaluation durch die Leibniz-Gemeinschaft zur weiteren Förderung empfohlen
- Raluca Niesner wurde zu Oktober 2018 zur Universitätsprofessorin am Fachbereich Veterinärmedizin der FU ernannt.
- Keynote Lecture of Andreas Radbruch at the 5th European Congress of Immunology
- Senioren – Zahlreiche Senioren haben rheumatische Erkrankungen wie Arthrose oder rheumatoider Arthritis. Wie können Sie gegensteuern?
- 30 Jahre Rheumaforschung in Berlin
- Die Darmflora als Spiegel der Gesundheit
- DGfZ Meeting in Jena: Poster award for Lisa Budzinski
- Transitionsprojekte
- „Tag der Immunologie“ am DRFZ
- DRFZ anniversary ceremony
- Vielen Dank für eine schöne, spannende Lange Nacht der Wissenschaften am DRFZ!
- Annual Report of the DRFZ is online in media library
- “Unser Ziel ist eine neue Klasse von Biologika” – Interview mit Andreas Radbruch
- Rheuma birgt hohes Risiko für Begleiterkrankungen
- From single cell observation to systemic understanding
- Arbeitsgruppe Kerndokumentation mit Kussmaul-Medaille der Deutschen Gesellschaft für Rheumatologie ausgezeichnet
- 2nd Leibniz Summer School – Connecting Concepts of Chronic Inflammation
- Fritz Melchers zum Ehrenmitglied der Deutschen Gesellschaft für Rheumatologie ernannt
- Rheuma bei Kindern oft schwer erkennbar
- Poster Award for Patrick Maschmeyer
- Andreas Radbruch becomes new President of the European Federation of Immunological Societies
- Advanced Cytometry Course at the ECI
- Outstanding research funding for two young female DRFZ scientists
- Dr. Mir-Farzin Mashreghi: Er sucht neue Wege gegen chronische Entzündungen
- A new Lichtenberg Professorship dedicated to intestinal tract immunity
Dates
- Avrion Mitchison Prize 2019
- Lange Nacht der Wissenschaften 2019 im DRFZ
- Leopoldina-Symposium – Environmental Education of the Immune System in Health and Disease
- Rheuma-Liga im DRFZ: Sozialrecht und Kinder-Reha
Seminare
- Marina Babic – Cac: Immune checkpoints as therapeutic targets in inflammation
- Randy Lindquist: Chronic inflammation at ectopic sites
- Florian Milatz: Übergewicht bei JIA (Epidemiologisches Doktorandenseminar)
- Kirsten Minden, Nadine Betenstehl: Komorbiditäten bei Erwachsenen mit juveniler idiopathischer Arthritis
- Mathias Mursell: Distinct survival niches for memory T helper cells in spleen and bone marrow
- Justus Ninnemann: Modulation of immune responses via targeting of host-microbiota interactions
- Tobias Brunner: Regulation of IL-33 receptor expression in T cell lineages
- Gitta Heinz: Next Generation Sequencing to investigate Immunity and Chronic Inflammation
- Kirsten Minden, Jens Klotsche, Florian Milatz: Beobachtungsstudien in der Kinderrheumatologie
- Marta Ferreira Gomes: The Importance of Fungal Infections – The Candida albicans Case
- Randy Lindquist: Chronic Inflammation at Ectopic Sites
- Frederik Heinrich: Analysis and Visualization of RNAseq Data
- Florian Milatz: Gesundheitsverhalten bei Jugendlichen mit juveniler idiopathischer Arthritis
- Martina Niewerth, Sascha Eulert: Erfassung der Versorgung neu an Rheuma erkrankter Kinder (ProKind)
- Christian Neumann: The transcription factor c-Maf shapes intestinal immune homeostasis by controlling regulatory T cell effector functions
- Johanna Callhoff: Sjögren: Langzeit-Daten der Kerndokumentation (Epidemiologisches Doktorandenseminar)
- Kirsten Minden, Martina Niewerth: Schnittstellenproblematik Kinder-/Erwachsenen-Rheumatologie
- Susann Schweitzer: JIA und Depression – Daten aus dem JUMBO-Register
- Laura Montag: Patientenberichtete Therapien bei der JIA (Epidemiologisches Doktorandenseminar)
- Michaela Heinrich: Bewertung der Versorgungssituation bei Patienten mit JIA (Epidemiologisches Doktorandenseminar)
- Jens Klotsche: Einfluss des Zeitpunktes des Therapiestartes mit Biologika auf die Langzeitprognose der JIA
- Annette Lahmann: Development and Maintenance of T Follicular Helper Cells
- Johanna Callhoff: Claims Data for Health Services Research in Chronic Inflammatory Diseases
- Caroline Helmstetter: Quality versus Quantity in T Cell Cytokine Production
- Stefan Frischbutter: Mast Cells in Chronic Inflammation
- Martin Schäfer: Obesity and Rheumatoid Arthritis – of Biology and Biologic Drugs
- Laleh Khodadadi: CAR-T Cell Therapy
- Yvette Meißner: Pregnancies in Patients with Spondyloarthritis
- Kevin Thurley: What can we learn from mathematical models in immunology?
- Andreas Diefenbach: The role of ILC3 in intestinal epithelial homeostasis
- Christopher Skopnik: Indications for autoreactivity of human T cells towards renal epithelial cells
- There will be no seminar on 6 August 2019, because of unavailability of the speaker. Apologies for any inconvenience!
- Timo Rückert: Mechanisms of generation and maintenance of cytomegalovirus-induced NKG2C+ NK cell expansions
- Thomas Rose: Type I IFN in idiopathic inflammatory myositis
- Domonkos Varga: Heterogeneity of cytotoxic T cell programs
- Rebecca Cornelis: Stromal cell contact-induced PI3K signaling prevents caspase-3 induced cell death of memory plasma cells
- Jason Biniaris: Regulation of Lupus Nephritis by group 1 innate lymphoid cells
- Caroline Helmstetter: Quantitative regulation of signature molecules in Th1 memory cells
- Irene Mattiola: The macrophage tetraspan MS4A4A interacts with Dectin-1 and is required for macrophage/NK cell cross-talk and resistance to metastasis
- Alexander Ferdinand Fiedler: Development of a longitudinal fluorescence lifetime microendoscopy method for analyzing the cell metabolism during bone regeneration
- Nayar Duran Hernandez: Immune cell populations in the Hoffa fat pad of patients with Knee osteoarthritis
- Axel Schulz: Immune cell profiling of rheumatoid arthritis patients undergoing helminth therapy by mass cytometry
- Marina Babic-Cac: NK cell receptor NKG2D enforces pro-inflammatory features and pathogenicity of Th1 and Th17 cells
- Ping Shen: TLR-1/2 signaling impairs mitochondrial oxidative phosphorylation in human chondrocytes via the induction of nitric oxide
- Sabine Kirchner: Adhärenz – Validierung eines Erhebungsinstrumentes
- Andreas Pelz: Antigen-specific plasma cell depletion in myasthenia gravis
- Andrey Kruglov: Regulation of innate immune system by cytokines during inflammation
- Alexandra Damerau: First steps towards the in vitro simulation of an arthritic joint
- Gitta Heinz: Rolling circle translation of a circular RNA in T helper lymphocytes
- Carolin Ulbricht: Linking BCR signaling to metabolic reprogramming in germinal center B cells
- Anna Rapp: Mouse models of osteoarthritis
- Ruth Leben: Dynamic and functional in vivo imaging using time-resolved fluorescence microscopy
- Patrick Maschmeyer: Transcriptional landscapes of memory T cells from patients with juvenile idiopathic arthritis
- Julia Kuhrau: Novel pathways controlling T follicular helper cells
- Marie Urbicht: Mass cytometry profiling of signaling pathways in SLE and during therapeutic intervention by JAK inhibitors
- Shintaro Hojyo: Antigen priming of XCR1+ dendritic cells preferentially guides the differentiation of resting memory CD4 T cells
- Marta Ferreira Gomes (Department of Cell Biology, Friedrich-Schiller-University Jena): Mechanism and effect of Candida albicans recognition by murine B cells
- Stefanie Gryzik: Immunomodulation of T helper cell subsets in an autoimmune model
- Shimon Sakaguchi, M.D., Ph.D.: Treg cells in autoimmune disease
- Christopher Kreßler: Epigenetic editing converts naïve and memory CD4+ T cells into FOXP3 expressing (regulatory ?) T cells
- Jonathan Stefanowski: Elucidating mechanisms of bone regeneration using longitudinal intravital microscopy in the bone marrow
- Martina Niewerth: Webbasierte Erfassung von Langzeitbeobachtungen in der Kinderrheumatologie (Epidemiologisches Doktorandenseminar)
- Svea Horn, Claudia Sengler: Juvenile Dermatomyositis – Daten aus der Kinderkerndokumentation (Epidemiologisches Doktorandenseminar)
- Claudia Sengler: Interpretation von Laborparametern in der Kinderrheumatologie (Epidemiologisches Doktorandenseminar)
- Tom Kolodziej, Florian Milatz: Sportprojekt „RheumaFit“ (Epidemiologisches Doktorandenseminar)
- Paula Drechsel: Verlauf und Outcomes von Schwangerschaften bei Erwachsenen mit juveniler idiopathischer Arthritis – Erste Ergebnisse
- Prof. Dr. Gerhard Krönke: Novel checkpoints during (Auto)antibody-induced inflammation
- Laura Bauer: T cell/B cell cooperation in inflamed lung tissue
- Seminar on ScaiVision
- Yen Hoang: PRI on cytometric data – proposing differentiating marker combinations based on machine learning
- Philipp Enghard: Urinary cells as biomarker for renal diseases
- Randall Lindquist: Intravital single-cell metabolic imaging of germinal centers
- Asylkhan Rakhymzhan: Three-photon imaging of various mouse organ structures
- Adrian Madrigal-Avilés: Different regulation in glucose metabolism between Th1 and Th2 cells
- Weijie Du: The epigenetic imprinting of human memory lymphocytes
- Anna Pascual-Reguant: Analysis of rare cell populations in situ using MELC
- Manuela Frese-Schaper: Topoisomerase I inhibitors as a potential new treatment for systemic lupus erythematosus
- Dominik Niesen: Quantitative stability of GATA3 and IL-4 expression levels in Th2 cells
- Siska Wilantri: Circadian rhythms of immune cells in healthy individuals and patients with Rheumatoid Arthritis
- Claudia Sengler: Juvenile dermatomyositis – data of a national pediatric rheumatology database
- Nils Geisemeyer: Operationalisierung von Geschlecht in Erhebungsinstrumenten
- Sabine Baumgart: Implementing mass cytometry in clinical research
- Laleh Khodadadi: Autoreactive long-lived plasma cells: From discovery to depletion!
- Ralf Köhler : Multiplexed fluorescence microscopy reveals heterogeneity among stromal cells in mouse bone marrow sections
- Daniel Schulz : The role of stromal niches in chronic inflammation
- Randy Lindquist: Imaging of inflammation
- Stefanie Hahne: PI3 kinase and NFkB signaling induced by stromal cells and APRIL synergize to balance expression of pro- and anti-apoptotic proteins for survival of longlived bone marrow plasma cells
- Gitta Heinz: RNA-based gene regulation in chronic inflammation
- Laleh Khodadadi : Targeting Plasma cells
- Axel Schulz : High-Parametric Mass Cytometry: A single-cell, system-level technology for deciphering chronic inflammatory diseases
- Yvette Meißner : Inflammation, rheumatoid arthritis and cardiovascular disease
- Jens Klotsche: Langzeitsicherheit einer Biologika-Therapie im Kindesalter (JUMBO) (Epidemiologisches Doktorandenseminar)
- Asylkhan Rakhymzhan: Optical methods
- Randy Lindquist: Chronic inflammation and cancer
- Yvette Meißner: Schwangerschaften unter PsA/SpA (EuNeP) (Epidemiologisches Doktorandenseminar)
- Imke Redeker, Denis Poddubnyy: Komorbidität in Proclair (Epidemiologisches Doktorandenseminar)
- Stefan Frischbutter: Drug Discovery in academia
- Rheumatology Research Talks: AG Triantafyllopoulou
- Patrick Maschmeyer: Functions of microRNAs in chronic inflammatory diseases
- Shintaro Hoyjo: Helper T cells in chronic inflammation
- Alexander Beller: Microbiota analysis in health and disease
Arbeitsgruppen
- Kallinich lab
- Baumgrass lab
- Kruglov lab
- Chang lab
- Kubagawa lab
- Melchers lab
- Radbruch lab
- Thurley lab
- Tokoyoda lab
- Buttgereit lab
- Diefenbach lab
- Dörner lab
- Hauser lab
- Hegazy lab
- Hiepe lab
- Hutloff lab
- Niesner lab
- Polansky-Biskup lab
- Romagnani lab
- Triantafyllopoulou lab
- Worm lab
- Minden lab
- Strangfeld lab
- Zink group
- Poddubnyy lab
- Mashreghi lab
- Löhning lab
- Mass Cytometry
- Flow Cytometry & Cell Sorting (FCCF)
- Central Laboratory for Microscopy (CINIMA)
- Regine von Ramin Lab Molecular Rheumatology
- Immune Monitoring
- Animal Facility
- Embryo Technology Laboratory
Köpfe
- Prof. Dr. Andreas Radbruch
- Petra Starke
- Prof. Dr. Angela Zink
- Prof. Dr. Ria Baumgrass
- Prof. Dr. med. Frank Buttgereit
- Dr. habil. Hyun-Dong Chang
- Univ.-Prof. Dr. Andreas Diefenbach
- Prof. Dr. med. Thomas Dörner
- Dr. rer. nat. Andreas Grützkau
- Prof. Dr. med. vet. Anja Erika Hauser
- Prof. Dr. med. Dr. rer. nat. Ahmed N. Hegazy
- Prof. Dr. med. Falk Hiepe
- Heike Hirseland
- Dr. rer. nat. Andreas Hutloff
- PD Dr. med. Tilmann Kallinich
- Antje Klauß
- Dr. Andrey Kruglov
- Prof. Dr. Hiromi Kubagawa
- Prof. Dr. Max Löhning
- Mag. Dr. Elke Luger
- Dr. Mir-Farzin Mashreghi
- Dr.rer. nat. Henrik Mei
- Prof. Dr. Fritz Melchers
- Prof. Dr. med. Kirsten Minden
- Dr. Katrin Moser
- Prof. Dr. rer. nat. Raluca Niesner
- Prof. Dr. Denis Poddubnyy
- Dr. Julia Polansky-Biskup
- Univ.-Prof. Dr. Chiara Romagnani
- Dr. med. Anja Strangfeld
- Dr. Kevin Thurley
- Dr. Koji Tokoyoda
- Dr. Antigoni Triantafyllopoulou
- Prof. Dr. med. Margitta Worm